Case-control study of family and behavioral factors for precocious puberty in girls
Objective To analyze the influencing factors of precocious puberty in girls,in order to provide evidence for children's healthcare.Methods A total of 177 precocious puberty girls treated in Tianjin Women and Children's Health Center between October 2019 and August 2022 were recruited as the case group,and 354 healthy girls matched 1∶2 by age were selected as the control group based on routine physical examination.Information of age,behavior factors were collected,height and body weight were recorded and body mass index(BMI)was calculated.The comparison between the two groups was performed using the t test or the x2 test.Logistic regression model was used to determine the potential influencing factors of precocious puberty.Results The average age of girls in case and control groups were(7.72±1.02)and(7.60±1.05)years old,respectively,and the difference was not significant(P＞0.05).Multivariate Logistic regression analysis showed that larger waist circumference(OR=1.11,95％CI:1.07-1.15),screen time＞1h/d(OR=4.35,95％CI:2.62-7.22),moderate-to-vigorous physical activity ≤ 1 h/d(OR=3.14,95％CI:1.71-5.75),and higher ratio of plastic bottled water(OR=1.02,95％CI:1.01-1.03)were risk factors,and mother's older age at menarche(OR=0.59,95％CI:0.45-0.76),father's older age of first spermatorrhea(OR=0.67,95％CI:0.53-0.85),and longer nap time(OR=0.97,95％CI:0.96-0.98)were protective factors for precocious puberty in girls(P＜0.05).Conclusion Health education should be strengthened to help children establish good behavior habits to reduce the risk of precocious puberty in girls.
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