Effects of prenatal stress on the neurobehavioral development of offspring
Pregnancy is a special period for women both physically and psychologically,during which they may experience various stressors.Persistent or severe prenatal stress not only adversely affects the mother,but also impairs the offspring's brain structure and function,increasing the risk of neuropsychological development disorders,such as depression,anxiety,attention deficit hyperactivity disorder,autism spectrum disorder,and learning and memory impairment,etc.This review summarizes the commonly used animal models of prenatal stress,and the research progress on the effects and mechanisms of prenatal stress on the development of offspring.In addition,the possible future research directions are discussed and prospected,so as to provide new ideas for the intervention of adverse neurobehavior in offspring after prenatal stress.
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