Obesity is a disease characterized by the accumulation of adipose tissue and metabolic dysregulation.The prevalence of childhood obesity is on the rise;however,the intricate mechanisms underlying changes in body weight and metabolism remain elusive.Metabolomics,a high-throughput and highly sensitive detection method,enables comprehensive analysis and identification of small molecules or metabolites in biological samples,thereky elucidating the relationship between childhood obesity and metabolism,facilitating the discovery of potential biomarkers and therapeutic targets while providing insights into the pathogenesis of childhood obesity and its associated complications.This review summarizes recent advances in metabolomics research pertaining to childhood obesity.