多巴胺及其受体在儿童抽动障碍中的作用
Role of dopamine and its receptors in tic disorder in children
邱佳琪 1钟霞 2邹时朴2
作者信息
- 1. 江西省儿童医院心理卫生科,江西 南昌 330000;南昌大学医学部,江西 南昌 330006
- 2. 江西省儿童医院心理卫生科,江西 南昌 330000
- 折叠
摘要
抽动障碍是以运动和/或发声抽动为特征的在儿童期发作的神经精神障碍,通常影响儿童的身心健康.抽动障碍的发病机制可能与皮质-纹状体-丘脑-皮质回路中的异常神经递质有关,尤其是儿茶酚胺类神经递质多巴胺.本文针对重要神经递质多巴胺及其受体在抽动障碍发病中的作用展开综述,以期为指导临床治疗和预防提供参考.
Abstract
Tic disorder is a childhood-onset neuropsychiatric disorder characterized by motor and/or vocal tics that commonly affect children's physical and mental health.The pathogenesis of tic disorders may be related to abnormal neurotransmitters in the cortico-striatal-thalamic-cortical loop,especially the catecholamine neurotransmitter dopamine.This article reviews the role of dopamine and its receptors in the pathogenesis of tic disorders,in order to provide reference for clinical treatment and prevention.
关键词
抽动障碍/抽动秽语综合征/多巴胺/多巴胺受体Key words
tic disorder/Tourette syndrome/dopamine/dopamine receptor引用本文复制引用
出版年
2024
NETL
NSTL
万方数据