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儿童过敏性疾病并发抽动障碍机制的研究进展

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在过去的几十年中,儿童过敏性疾病在全球范围内的发病率逐年升高,其对患儿的影响已经超出了过敏本身。有证据表明儿童过敏性疾病与抽动障碍的发生发展具有相关性。并且过敏性疾病可能是抽动障碍的重要危险因素。其发生机制可能与肠道微生态紊乱、免疫学特征改变以及DNA甲基化相关。深入探讨儿童过敏性疾病和抽动障碍之间的关系,将对预防和治疗抽动障碍具有重要意义。
Advances in the possible mechanisms of tic disorders comorbid with allergic diseases in children
In the past few decades,the incidence rate of children's allergic diseases in the world has been gradually increasing worldwide,and its impact on children has exceeded the condition of allergy itself.There is evidence suggesting a correlation between allergic diseases and the different of tic disorder(TD)in children,and allergies may be an important risk factor of TD.The underlying mechanism may be related to intestinal microbiota disorders,changes in immunological characteristics,and DNA methylation.Further exploration of the relationship between allergic diseases and TD will be of great significance for the prevention and treatment of TD.

allergic diseasestic disorderintestinal microbiotaimmunological characteristicsDNA methylationchildren

张盼盼、曹凡、肖绪武

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大连市妇女儿童医疗中心(集团)儿童保健科,大连医科大学,辽宁 大连 116011

过敏性疾病 抽动障碍 肠道微生态 免疫学特征 DNA甲基化 儿童

2024

中国儿童保健杂志
西安交通大学,中华预防医学会

中国儿童保健杂志

CSTPCD北大核心
影响因子:1.199
ISSN:1008-6579
年,卷(期):2024.32(12)