In the past few decades,the incidence rate of children's allergic diseases in the world has been gradually increasing worldwide,and its impact on children has exceeded the condition of allergy itself.There is evidence suggesting a correlation between allergic diseases and the different of tic disorder(TD)in children,and allergies may be an important risk factor of TD.The underlying mechanism may be related to intestinal microbiota disorders,changes in immunological characteristics,and DNA methylation.Further exploration of the relationship between allergic diseases and TD will be of great significance for the prevention and treatment of TD.
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