首页|围绝经期异常子宫出血患者伴子宫内膜病变危险因素及预测效能研究

围绝经期异常子宫出血患者伴子宫内膜病变危险因素及预测效能研究

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目的 探讨围绝经期异常子宫出血患者伴子宫内膜病变危险因素并评估预测效能,旨在为早期识别高危人群及制定个体化防治方案提供借鉴。方法 回顾性纳入2017年1月至2022年6月于安徽医科大学附属巢湖医院诊治围绝经期异常子宫出血患者共102例,根据是否伴子宫内膜病变分组,评估围绝经期异常子宫出血患者伴子宫内膜病变的独立危险因素,描绘受试者工作特征(ROC)曲线分析上述独立危险因素用于患者伴子宫内膜病变风险的临床效能。结果 单因素和多因素分析结果显示,年龄增加与合并2型糖尿病(T2DM)均是围绝经期异常子宫出血患者伴子宫内膜病变的独立危险因素(P<0。05);ROC曲线分析结果显示,年龄与合并T2DM均可用于围绝经期异常子宫出血患者伴子宫内膜病变的风险预测,且两者联合预测效能优于单一指标(P<0。05)。结论 围绝经期异常子宫出血患者伴子宫内膜病变可能与年龄及合并T2DM情况有关;而以上两项指标联合能够更为有效地预测患者伴子宫内膜病变的发生风险。
Risk factors and predictive efficacy of secondary endometrial lesions in perimenopausal patients with abnormal uterine bleeding
Objective To investigate the risk factors and predictive efficacy of secondary endometrial lesions in perimenopausal patients with abnormal uterine bleeding to provides reference for early identification of high-risk groups and individualized prevention and treatment programs.Methods 102 perimenopausal patients with abnormal uterine bleeding were retrospectively selected from January 2017 to June 2022 in Chaohu Hospital affiliated to Anhui Medical University.All patients were divided into different groups according to whether secondary endometrial lesion or not.To evaluate the independent risk factors for secondary endometrial lesions in perimenopausal patients with abnormal uterine bleeding Receiver operating characteristic(ROC)curves were plotted to analyze the clinical efficacy of these independent risk factors in patients with secondary endometrial disease.Results Univariate and.multivariate analysis showed that age and combined with T2DM were independent risk factors for secondary endometrial lesions in patients with perimenopausal abnormal uterine bleeding(P<0.05).ROC curve analysis showed that both age and T2DM could be effectively predict the risk of secondary endometrial lesions in perimenopausal patients with abnormal uterine bleeding.Notably,the combined use of these two indicators yielded superior predictive efficacy compared to using either indicator alone(P<0.05).Conclusion The secondary endometrial lesions of perimenopausal patients with abnormal uterine bleeding may be related to age and T2DM and the combination of the above two indexes can more effectively predict the secondary endometrial lesions risk in patients above.

perimenopauseabnormal uterine bleedingendometrial lesionsrisk factorspredictive efficacy

陈君墨、郑贤芳

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安徽医科大学附属巢湖医院妇科,合肥 238000

围绝经期 异常子宫出血 子宫内膜病变 危险因素 预测效能

安徽医科大学科研项目

2019xkj163

2024

中国妇产科临床杂志
北京大学

中国妇产科临床杂志

CSTPCD北大核心
影响因子:1.095
ISSN:1672-1861
年,卷(期):2024.25(1)
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