Evaluation of home-based human papillomavirus self-sampling in rural women
Objective To explore the effects of home-based HPV self-sampling in rural women.Methods From June 2022 to November 2022,600 rural women were recruited in Hangzhou and Jiaxing in Zhejiang Province,and included in the study group(n=257,HPV home self-sampling)and control group(n=286,HPV site self-sampling)respectively by non-random grouping method.Both groups completed the HPV self-sampling cognition,experience and acceptance survey.The sampling success rate,sample acceptance rate within 7 days,qualification rate and the cognition,experience and acceptance were compared.Results The sample success rate between the study group(98.44%,253/257)and the control group(98.95%,283/286)had no significant difference(P>0.05).There was no significant difference in sample qualification rate between the study group(98.05%,252/257)and the control group(98.95%,283/286).The sample acceptance rate of the control group(100.00%,286/286)within 7 days was higher than the study group(97.67%,251/257)and the difference was statistically significant(P<0.05).A total of 214 cases(83.27%)in the study group and 255 cases(89.16%)in the control group completed the HPV self-sampling questionnaire.Rural women having accepted advanced education and the"two cancers"screening,with high cognition,and experience were more willing to choose self-sampling(P<0.05).Conclusions The effect of home-based HPV self-sampling in rural women is similar to site-based self-sampling.Rural women with high,cognition and experience degree of HPV self-sampling,and participating of the"two cancers"screening were more willing to choose HPV self-sampling.