Objective The analysis showed the value of predicting non-estrogen-dependent endometrial cancer based on preoperative MRI radiomic characteristics.Methods A total of 160 patients with endometrial cancer admitted to The First Affiliated Hospital of Bengbu Medical College from January 2018 to May 2023 were selected as the study objects,80 patients diagnosed with non-estrogen-dependent endometrial cancer were selected as the study group,and the remaining 80 patients with estrogen-dependent endometrial cancer were selected as the control group.All subjects underwent MRI examination and serum carbohydrate antigen 125(CA125),carbohydrate antigen 153(CA 153)and carcinoembryonic antigen(CEA)levels were detected before surgery.Results Compared with the control group,the maximum diameter of tumor in the study group was higher,the Apparent diffusion coefficients(ADC)mean level was lower,and the proportion of diffuse type was higher.In the study group,the boundary was blurred,the T1WI signal was equal or slightly lower,the T2WI signal was mixed with high signal,and the DWI signal was slightly higher(P＞0.05).Compared with patients with stage Ⅰ to Ⅱ non-estrogen-dependent endometrial carcinoma,patients with stage Ⅲ to Ⅳ non-estrogen-dependent endometrial carcinoma had higher tumor maximum diameter,higher serum CA125,CA153 and CEA levels,and lower ADCmean levels(P＜0.05).Compared with MRI parameters of maximum tumor diameter,ADCmean,CA125,CA153 and CEA,combined diagnosis had higher sensitivity,specificity and accuracy in predicting non-estrogen-dependent endometrial carcinoma(P＜0.05).Conclusion MRI radiomic features combined with serum CA125,CA153 and CEA have high value in predicting non-estrogen-dependent endometrial carcinoma.
维普
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