Objective To analyze the relevant factors that affect the effectiveness of high uterineeaezeligatlon suspensien(HUS)in treating postpartum stage Ⅲ～Ⅳ pelvic organ prolapse(POP).Methods The medical records of postpartum patients with grade Ⅲ～Ⅳ POP who were admitted to the hospital for HUS from August 2019 to August 2022 in the obstetrics and gynecology database of 903 Hospital of the Chinese People's Liberation Army Joint Logistic Support Force were retrieved for retrospective study.The patients were divided into the ineffective group(n=26)and the effective group(n=188)according to the clinical efficacy one year after surgery.The data of the two groups were collected to analyze the factors affecting the effect of HUS in the treatment of postpartum Ⅲ～Ⅳ POP.Results Univariate and multivariate Logistic regression analysis showed that history of vaginal delivery(OR=11.909),abnormal increase of serum relaxin level(OR=1.167)and abnormal increase of matrix metalloproteinase-1(MMP-1)level(OR=11.656)were risk factors affecting the effect of HUS in the treatment of postpartum Ⅲ～Ⅳ POP,while regular sexual activity after surgery(OR=0.043)was a protective factor.Conclusions The effectiveness of HUS in the treatment of postpartum stage Ⅲ～Ⅳ POP is influenced by comprehensive factors such as vaginal delivery frequency,postoperative regular lifestyle,serum relaxin and MMP-1 levels.It is recommended to provide targeted early education and intervention treatment to improve the effect of surgical treatment.
关键词
盆腔脏器脱垂/盆底重建术/阴道分娩/松弛素
Key words
pelvic organ prolapse/pelvic floor reconstruction surgery/vaginal delivery/relaxin
维普
万方数据