Analysis of micronucleus rate in 394 radiation workers with cytokinesis-block micronucleus method
Objective To analyze the micronucleus rate of radiation workers and to provide accurate occupational health monitoring basis in radiation workers exposed to low-level ionizing radiation for a long time.Methods The radiation group consisted of 353 radiation workers who had been exposed to ionizing radiation during work,while the control group con-sisted of 41 radiation workers who had not yet been exposed to ionizing radiation before work.The cytokinesis-block micro-nucleus method was used to determine the micronucleus rate.Results The average micronucleus rate in the radiation group was significantly higher than that in the control group(t=-2.95,P＜0.05).In the radiation group,the micronucleus rate gradually increased with age,and the difference was statistically significant(F=8.36,P＜0.05).The micronucleus rates of workers with＞10 and＞30 years of service were significantly higher than those of workers with＜10 years of service(x2=-44.79,-60.47,P＜0.05).The micronucleus rate in females was significantly higher than that in males(t=3.93,P＜0.05).The micronucleus rates in the diagnostic radiology group and the industrial detection group were significantly higher than that in the control group(t=3.51,3.65,P＜0.05).Conclusion The micronucleus rate has increased among the radiation workers exposed to low-level ionizing radiation for a long time.It is necessary to further strengthen occupational health mon-itoring and radiation protection education for radiation workers,especially the medical workers that constitute the largest population of radiation exposure workers.
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