Analysis of factors influencing lymphocyte micronucleus in industrial radiation workers in Gansu Province,China
Objective To analyze micronucleus abnormalities in the peripheral blood lymphocytes of industrial radiation workers and the influencing factors,and to provide a reference for radiation protection.Methods The occupational health monitoring data of 661 industrial radiation workers were collected from the occupational health examination system of Gansu Provincial Center for Disease Control and Prevention.The abnormalities in the micronucleus of peripheral blood lymphocytes were analyzed.The influencing factors were identified by logistic regression.Results The micronucleus ab-normality rate was 6.05％for the 661 industrial radiation workers.There was no significant difference in micronucleus ab-normality rate between sexes(P＞0.05).Comparison of age groups showed that the rate of micronucleus abnormality in-creased with age,and workers over 50 years of age has the highest rate of micronucleus abnormalities(17.81％);there was a significant difference between age groups(P＜0.05).There was a significant difference in micronucleus abnormality rate between occupational categories(P＜0.05).There was a significant difference in micronucleus abnormality rate between groups with different years of work(P＜0.05).Logistic regression analysis showed that age and years of work were the risk factors for micronucleus abnormality rate(P＜0.05);age was an independent risk factor for micronucleus abnormality rate(P＜0.05).Conclusion The effect of low-dose ionizing radiation on micronucleus abnormality rate of industrial radiation workers is related to age and working years.Attention should be paid to occupational health monitoring of radiation workers,especially those with advanced age.
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