Research progress on animal models of combined radiation-wound injury
A combined radiation-wound injury refers to a radiation injury combined with a traumatic wound,with the char-acteristics of repeated ulceration and a long and difficult healing process,which is a focus in the field of research on difficult-to-heal wounds.To research combined radiation-wound injuries,the establishment of animal models is a key part,and appro-priate animal models are a guarantee of reliable experimental results.This review summarizes the current research progress on various animal models of combined radiation-wound injuries in terms of radiation types,animal species,and injury types and location,aiming to provide a scientific basis for establishing standardized animal models,studying injury mechanisms,and evaluating prevention and treatment efficacy for combined radiation-wound injuries.
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