Advances in CT-based study of lymphatic drainage and mediastinal lymph node metastasis in non-small cell lung cancer
Mediastinal lymph node metastasis is a common metastasis pathway of non-small cell lung cancer(NSCLC),and its occurrence is closely related to lymphatic drainage pattern.NSCLC in different pulmonary lobes requires different lymph-atic drainage patterns,which poses a challenge for the formulation of individualized treatment strategies.Accurate staging is the prerequisite for precision treatment of NSCLC.Computed tomography(CT)examination is an important tool for evaluat-ing mediastinal lymph node metastasis,which is crucial for making treatment plan and evaluating patient prognosis.However,it is difficult to diagnose metastatic lymph nodes with insignificant imaging features,especially metastatic lymph nodes in zone 4 and zone 7,which are hot spots for mediastinal lymph node metastasis.However,clinical guidelines do not make clear provisions on lymph node dissection in zone 4,which makes preoperative clinical staging and prognosis evalu-ation of patients with NSCLC particularly important.By integrating and analyzing a large amount of data in CT images,the emerging CT radiomics technology captures subtle features that may be overlooked in conventional CT scans,showing great application prospects in improving the accuracy of non-invasive diagnosis of lymph node metastasis.This review aims to ex-plore the mediastinal drainage pattern and the role of CT in evaluating mediastinal lymph node metastasis,in order to provide valuable imaging evidence for accurately judging mediastinal lymph node metastasis of NSCLC,formulating appropriate lymph node dissection scope,optimizing treatment strategy,and improving patient prognosis.
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