首页|2018—2022年广西壮族自治区柳州市围产儿出生缺陷医院监测结果分析

2018—2022年广西壮族自治区柳州市围产儿出生缺陷医院监测结果分析

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目的 了解 2018—2022年广西壮族自治区柳州市围产儿出生缺陷发生特征及变化趋势,为科学防控出生缺陷提供参考依据.方法 采用回顾性研究方法,对 2018—2022年在广西壮族自治区柳州市各助产机构出生的孕满 28周至产后 7 d内的围产儿出生缺陷监测数据进行分析.结果 2018—2022年柳州市围产儿 212 475例,出生缺陷儿 3 406例,总出生缺陷发生率为 160.30/万,出生缺陷发生率先下降后上升.男婴出生缺陷平均发生率为 176.06/万,女婴出生缺陷平均发生率为142.43/万,男婴出生缺陷发生率高于女婴(χ2 = 36.821,P<0.001);≥35岁母亲子代出生缺陷发生率(201.91/万)较年轻母亲高,孕 1次(174.44/万)和产 1次(189.21/万)的母亲子代出生缺陷发生率均高于孕产≥2次的母亲,多胎出生缺陷发生率(433.66/万)高于单胎(152.65/万),差异均有统计学意义(均P<0.05).发生率较高的前 5位出生缺陷为先天性心脏病(68.95/万)、多指/多趾(31.06/万)、尿道下裂(9.51/万)、并指/并趾(9.08/万)、外耳其他畸形(8.71/万).结论 2018—2022年柳州市围产儿出生缺陷发生率仍处于较高水平,以先天性心脏病与多指/多趾为高发.建议进一步加强和完善该地区出生缺陷防控三级预防体系建设,以进一步预防出生缺陷的发生.
Analysis on surveillance data of perinatal birth defects in Liuzhou,Guangxi Zhuang Autonomous Region,2018-2022
Objective To explore the trend and epidemiological features of perinatal birth defects in Liuzhou,Guangxi Zhuang Autonomous Region from 2018 to 2022,so as to provide evidence for scientific prevention and control of birth defects.Methods Retrospective research method was used to analyze perinatal birth defect surveillance data,which were born in various midwifery institutions from 28 weeks to 7 days postpartum at Liuzhou,Guangxi Zhuang Autonomous Region,2018-2022.Results Totally,3 406 infants with birth defects were found among 212 475 perinatal newborns from 2018 to 2022,and the incidence of birth defects was 160.30/10 000.The incidence of birth defects first declined and then rose.The average incidence of birth defects of boy was 176.06/10 000,which was significantly higher than that of girl(142.43/10 000)(χ2 = 36.821,P<0.001).Higher incidence of birth defects showed in the offspring of mothers aged≥35 years(201.91/10 000)compared to younger mothers(P<0.05).The incidence of birth defects in the offspring of mothers who had 1 pregnancy(174.44/10 000)and 1 birth(189.21/10 000)was higher than that of mothers who had≥2 pregnancies and births(P<0.05).The incidence of birth defects in multiple births(433.66/10 000)was higher than that in singleton births(152.65/10 000)(P<0.05).The top 5 birth defects were congenital heart diseases(68.95/10 000),multiple fingers/toes(31.06/10 000),hypospadias(9.15/10 000),syndactyly(9.08/10 000)and other outer ear deformities(8.71/10 000).Conclusion The incidence of perinatal birth defects remains at a relatively high level in Liuzhou,2018-2022.Congenital heart diseases and multiple fingers/toes are the most common birth defects.It is recommended to further improve the construction of the three-tier prevention system for birth defect prevention and control.

perinatalbirth defectsincidence

雷金梦、农铮、关海滨、曾定元、蒋明娟、周波

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广西医科大学,广西 南宁 530021

广州市妇女儿童医疗中心柳州医院,广西 柳州 545616

柳州市妇幼保健院,广西 柳州 545001

广西妇产疾病临床医学研究中心,广西 柳州 545001

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围产儿 出生缺陷 发生率

广西科技计划项目-广西妇产疾病临床医学研究中心

桂科AD22035223

2024

中国妇幼卫生杂志

中国妇幼卫生杂志

影响因子:0.533
ISSN:
年,卷(期):2024.15(1)
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