The purpose of this paper is reveal the biological activity of its aboveground stem,its pericarp and bulb of the three parts form water chestnut.The ultrasonic assisted extraction method was used to obtain the water extract and alcohol extract of three parts of Eleocharis dulcis.With its ability to eliminate DPPH,ABTS+free radicals,its inhibition zone and minimum inhibitory concentration against Staphylococcus aureus,Escherichia coli,Saccharomyces cerevisiae and Aspergillus niger,and its inhibitory effect on α-glucosidase and α-amylase was evaluated for its antioxidant,antibacterial,and in vitro hypoglycemic activities;At the same time,we used Drosophila type Ⅱ diabetes model to investigate the hypoglycemic and lipid-lowering effects in vivo of three parts of water chestnut.The results showed that the extracts of three parts of E.dulcis all had DPPH,ABTS+radical scavenging ability,and the inhibitory ability of α-glucosidase,α-amylase with a dose-effect relationship,and the water extract of pericarp from water chestnut has the strongest antioxidant effect while the water extract of its aboveground stem had the strongest hypoglycemic effect in vitro.In addition to A.niger,the extract from three parts of water chestnut had certain antibacterial effect on the other three kinds of bacteria,especially on S.aureus.The extracts from all three parts of water chestnut could reduce the contents of trehalose and triglyceride in Drosophila melanogaster,and had no significant effect on the contents of total protein while the water chestnu pericarp had the strongest hypoglycemic effect,and bulb of water chestnut had the strongest hypolipic effect.
关键词
马蹄三部位/抗氧化性/抑菌性/果蝇Ⅱ型糖尿病模型/降糖降脂作用
Key words
Three parts of water chestnut/antioxidant activity/antibacterial activity/drosophila type Ⅱ diabetes model/hypoglycemic and lipid-lowering effects
维普
万方数据