The cucumber powdery mildem is an important fungal disease in cucumber production.In order to select efficient fungicides to control the disease and offer a useful reference in future,this study used 70%thiophanate-methyl(WP),50%kresoxim-methyl(WG),42.8%triflumizole-trifloxystrobin(SC)and 20%penthiopyrad(SC)as the test drugs,and Xintai'Mici cucumber'as the test variety to conduct a pesticide control experiment on cucumber powdery mildew.The results showed that the four fungicides had the good control efficacy against the cucumber powdery mildem and had no bad effect.The 42.8%triflumizole-trifloxystrobin(SC)was the best fungicide to control the disease.The control efficacy were 83.92%and 75.25%after after 7 days and 14 days of spraying fungicide,there were significant difference among them.It was suggested to spray 2 or 3 times to control the disease and there was a 7 day interval between 2 times in the controlling process,at the same time 20%penthiopyrad(SC)was the alternative agent to use in order to avoid the drug-resistance of the pathogen.