首页|槐角丸联合地奥司明片治疗混合痔的疗效观察

槐角丸联合地奥司明片治疗混合痔的疗效观察

Clinical Efficacy of Huaijiao Pill Combined with Diosamine Tablet in Treatment of Mixed Hemorrhoids

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目的:观察槐角丸联合地奥司明片治疗混合痔的疗效.方法:选取2020年3月至2023年3月我院门诊收治的混合痔患者82例,将其分为对照组40例和观察组42例.对照组患者口服地奥司明片治疗,观察组在此基础上联用槐角丸治疗,2组均治疗4周,比较2组患者的疗效,疼痛评分、出血评分、肛缘水肿评分,血清炎症因子水平以及生活质量.结果:治疗后观察组患者总有效率明显高于对照组(P<0.05);治疗前2组患者疼痛评分、出血评分、肛缘水肿评分比较差异无统计学意义(P>0.05),治疗后2组患者疼痛评分、出血评分、肛缘水肿评分均低于治疗前,且观察组低于对照组(P<0.05);治疗前2组患者白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、高敏C反应蛋白(hs-CRP)水平比较差异无统计学意义(P>0.05),治疗后2组患者IL-6、TNF-α、hs-CRP水平均低于治疗前,且观察组低于对照组(P<0.05);治疗前2组患者生活质量评分比较差异无统计学意义(P>0.05),治疗后2组患者生活质量评分明显高于治疗前,且观察组高于对照组(P<0.05).结论:采用槐角丸联合地奥司明片治疗混合痔具有较好的临床疗效,可减轻患者疼痛、水肿,减少出血,降低血清炎症因子水平,提高生活质量.
Objective To observe the clinical efficacy of Huaijiao Pill combined with diosamine tablet in the treatment of mixed hemorrhoids.Methods A total of 82 patients with mixed hemorrhoids admitted to the Outpatient Department of our hospital from March 2020 to March 2023 were divided into the control group(40 cases)and the observation group(42 cases).The control group was treated with diosamine tab-let orally,while the observation group was treated with Huaijiao Pill on this basis,and both groups were treated for 4 weeks.The efficacy,pain score,bleeding score,anal edema score,serum inflammatory factor level and quality of life(QOL)of the two groups were compared.Results After treatment,the total ef-fective rate of the observation group was significantly higher than that of the control group(P<0.05).There were no significant differences in pain score,bleeding score and anal edge edema score between the two groups before treatment(P>0.05).After treatment,pain score,bleeding score and anal edge edema score of the two groups were lower than those before treatment,which were lower in the observation group than in the control group(P<0.05).There were no significant differences in the levels of interleu-kin-6(IL-6),tumor necrosis factor-α(TNF-α)and high-sensitive C-reactive protein(hs-CRP)between the two groups before treatment(P>0.05),and the levels of IL-6,TNF-α and hs-CRP of both groups after treatment were lower than those before treatment,which were lower in the observation group than in the control group(P<0.05).There was no significant difference in QOL score between the two groups be-fore treatment(P>0.05).QOL score of both groups after treatment was significantly higher than that before treatment,which was higher in the observation group than in the control group(P<0.05).Con-clusion The treatment of mixed hemorrhoids with Huaijiao Pill and diosamine tablet has good clinical effi-cacy,which can alleviate pain and edema,reduce bleeding,serum inflammatory factors and improve the quality of life.

Mixed hemorrhoidsHuaijiao PillDiosamine tabletsClinical efficacy

边防、龚静国、吴鸽

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洛阳市周山医院(河南 洛阳 471003)

混合痔 槐角丸 地奥司明片 疗效观察

2024

中国肛肠病杂志
中华中医药学会肛肠分会 山东中医药学会

中国肛肠病杂志

影响因子:0.131
ISSN:1000-1174
年,卷(期):2024.44(1)
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