Objective To analyze the risk factors of rotavirus enteritis in children and summarize the in-tervention measures.Methods Total 83 children with diarrhea admitted to our hospital from January 2022 to December 2023 were selected and divided into infection group(35 cases)and non-infection group(48 cases)according to whether rotavirus infection was present.The clinical data of the two groups were compared,and the factors with P<0.05 were further analyzed by Logistic regression.The risk factors of rotavirus enteritis in children were analyzed and the corresponding intervention measures were proposed.Results There was no significant difference in age,gender,feeding style,vitamin A supplement and vita-min D supplement between two groups(P>0.05).The observation group lived in rural areas,was taken care of by the elderly,spent less than 1 hour outdoors every day,had poor hand hygiene,contact history of rotavirus enteritis and malnutrition,and the proportion of children with the above characteristics was high-er in the observation group than in the control group(P<0.05).Logistic regression analysis showed that living in rural areas,taken care of by the elderly,daily outdoor activity time less than 1 hour,poor hand hygiene of children and their families,contact history of rotavirus enteritis,and malnutrition were risk fac-tors for rotavirus enteritis(P<0.05).Conclusion Living in rural areas,taken care of by the elderly,daily outdoor activity time less than 1 hour,poor hand hygiene of children and their families,contact histo-ry of rotavirus enteritis,and malnutrition are independent risk factors for children with rotavirus enteritis.Targeted preventive measures should be developed for children with independent risk factors to reduce the incidence of rotavirus enteritis.