Value of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Predicting Benign and Malignant Colorectal Tumors
Objective To investigate the value of neutrophil to lymphocyte ratio(NLR)and platelet to lymphocyte ratio(PLR)in predicting benign and malignant colorectal tumors.Methods A total of 80 cases of colorectal adenocarcinoma and 80 cases of colorectal adenoma admitted to our hospital from Janu-ary to December 2023 were selected as the study objects.The differences of general data(gender,age,co-morbidity,etc.)and laboratory indicators(globulin,albumin,hemoglobin,albumin to globulin ratio,NLR,PLR)between the colorectal adenocarcinoma group and the colorectal adenoma group were compared.Logistic regression was used to analyze independent factors related to benign and malignant colorectal tumors,and receiver operating characteristic(ROC)curve was used to analyze the efficacy of NLR and PLR in the diagnosis of benign and malignant colorectal tumors.Results There were no significant differences in gender,comorbidity and globulin level between the two groups(P＞0.05).However,the levels of albumin and hemoglobin,the ratio of albumin to globulin in the colorectal adenocarcinoma group were significantly lower than those in the colorectal adenoma group,while age,PLR and NLR were signifi-cantly higher than those in the colorectal adenoma group(P＜0.05).Logistic regression analysis showed that PLR and NLR were independent factors associated with benign and malignant colorectal tumors(P＜0.05).ROC curve showed that the cut-off value,the area under the curve(AUC),the sensitivity and the specificity of NLR and PLR in the diagnosis of colorectal adenocarcinoma and colorectal adenoma were 2.31 and 175.80,0.740 and 0.731,65.0％and 72.0％,88.5％and 81.5％,respectively.The AUC,the sen-sitivity and the specificity of NLR combined with PLR in the diagnosis of colorectal adenocarcinoma and adenoma was 0.765,74.6％and 90.4％,respectively.Conclusion Both NLR and PLR have certain value in predicting benign and malignant colorectal tumors,and the combination of them can work better.
Neutrophil to lymphocyte ratioPlatelet to lymphocyte ratioColorectal tumorBenign and malignantPrediction
NETL
NSTL
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