首页|Associations of sleeping patterns and isotemporal substitution of other behavior with the prevalence of CKD in Chinese adults

Associations of sleeping patterns and isotemporal substitution of other behavior with the prevalence of CKD in Chinese adults

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Studies have found a U-shaped relationship between sleep duration and chronic kidney disease(CKD)risk,but limited research evaluated the association of reallocating excessive sleep to other behavior with CKD.We included 104 538 participants from the nationwide cohort of the Risk Evaluation of Cancers in Chinese Diabetic Individuals:A Longitudinal Study,with self-reported time of daily-life behavior.Using isotemporal substitution models,we found that substituting 1 h of sleeping with sitting,walking,or moderate-to-vigorous physical activity was associated with a lower CKD prevalence.Leisure-time physical activity displacement was associated with a greater prevalence reduction than occupational physical activity in working population.In stratified analysis,a lower CKD prevalence related to substitution toward physical activity was found in long sleepers.More pronounced correlations were observed in long sleepers with diabetes than in those with prediabetes,and they benefited from other behavior substitutions toward a more active way.The U-shaped association between sleep duration and CKD prevalence implied the potential effects of insufficient and excessive sleep on the kidneys,in which the pernicious link with oversleep could be reversed by time reallocation to physical activity.The divergence in the predicted effect on CKD following time reallocation to behavior of different domains and intensities and in subpopulations with diverse metabolic statuses underlined the importance of optimizing sleeping patterns and adjusting integral behavioral composition.

sleepphysical activitychronic kidney diseaseisotemporal substitutionbehavioral pattern

Yi Ding、Xiaoli Xu、Zhuojun Xin、Qiuyu Cao、Jiaojiao Huang、Xianglin Wu、Yanan Huo、Qin Wan、Yingfen Qin、Ruying Hu、Lixin Shi、Qing Su、Xuefeng Yu、Li Yan、Guijun Qin、Xulei Tang、Gang Chen、Min Xu、Tiange Wang、Zhiyun Zhao、Zhengnan Gao、Guixia Wang、Feixia Shen、Zuojie Luo、Li Chen、Qiang Li、Zhen Ye、Yinfei Zhang、Chao Liu、Youmin Wang、Tao Yang、Huacong Deng、Lulu Chen、Tianshu Zeng、Jiajun Zhao、Yiming Mu、Shengli Wu、Yuhong Chen、Jieli Lu、Weiqing Wang、Guang Ning、Yu Xu、Yufang Bi、Mian Li

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Department of Endocrine and Metabolic Diseases,Shanghai Institute of Endocrine and Metabolic Diseases,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China

Shanghai National Clinical Research Center for Metabolic Diseases,Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of China,Shanghai Key Laboratory for Endocrine Tumor,State Key Laboratory of Medical Genomics,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200

Jiangxi Provincial People's Hospital,Affiliated to Nanchang University,Nanchang 330000,China

Department of Endocrinology,The Affiliated Hospital of Southwest Medical University,Luzhou 646000,China

Department of Endocrinology,The First Affiliated Hospital of Guangxi Medical University,Nanning 530000,China

Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou 310000,China

Department of Endocrinology,Affiliated Hospital of Guiyang Medical University,Guiyang 550000,China

Xinhua Hospital,Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200000,China

Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430000,China

Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510000,China

Department of Endocrinology,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China

Department of Endocrinology,The First Hospital of Lanzhou University,Lanzhou 730000,China

Fujian Provincial Hospital,Fujian Medical University,Fuzhou 350000,China

Dalian Municipal Central Hospital,Affiliated of Dalian Medical University Dalian 116000,China

Department of Endocrinology,The First Hospital of Jilin University,Changchun 130000,China

Department of Endocrinology,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000,China

Qilu Hospital of Shandong University,Jinan 250000,China

Department of Endocrinology,The Second Affiliated Hospital of Harbin Medical University,Harbin 150000,China

Department of Endocrinology,Central Hospital of Shanghai Jiading District,Shanghai 200000,China

Department of Endocrinology,Jiangsu Province Hospital on Integration of Chinese and Western Medicine,Nanjing 210000,China

Department of Endocrinology,The First Affiliated Hospital of Anhui Medical University,Hefei 230000,China

Department of Endocrinology,The First Affiliated Hospital of Nanjing Medical University Nanjing 210000,China

Department of Endocrinology,The First Affiliated Hospital of Chongqing Medical University,Chongqing 410000,China

Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430000,China

Shandong Provincial Hospital,Affiliated to Shandong University,Jinan 250000,China

Department of Endocrinology,Chinese People's Liberation Army General Hospital,Beijing 100000,China

Department of Endocrinology,Karamay Municipal People's Hospital,Karamay 834000,China

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国家自然科学基金国家自然科学基金国家自然科学基金国家自然科学基金国家自然科学基金Shanghai Rising-Star ProgramShanghai Outstanding Academic Leaders PlanNational Top Young Scholar ProgramInnovative Research Team of High-level Local Universities in ShanghaiShanghai Clinical Research Center for Metabolic Diseases上海申康医院发展中心项目上海申康医院发展中心项目

820881029185720582022011819707288193002121QA140810020XD142280019MC1910100SHDC2020CR1001ASHDC2020CR3064B

2024

医学前沿
高等教育出版社

医学前沿

CSTPCD
影响因子:1.362
ISSN:2095-0217
年,卷(期):2024.18(2)
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