首页|Association between ICU quality and in-hospital mortality of V-V ECMO-supported patients-the ECMO quality improvement action(EQIA)study:a national cohort study in China from 2017 to 2019

Association between ICU quality and in-hospital mortality of V-V ECMO-supported patients-the ECMO quality improvement action(EQIA)study:a national cohort study in China from 2017 to 2019

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This cohort study was performed to explore the influence of intensive care unit(ICU)quality on in-hospital mortality of veno-venous(V-V)extracorporeal membrane oxygenation(ECMO)-supported patients in China.The study involved all V-V ECMO-supported patients in 318 of 1700 tertiary hospitals from 2017 to 2019,using data from the National Clinical Improvement System and China National Critical Care Quality Control Center.ICU quality was assessed by quality control indicators and capacity parameters.Among the 2563 V-V ECMO-supported patients in 318 hospitals,a significant correlation was found between ECMO-related complications and prognosis.The reintubation rate within 48 hours after extubation and the total ICU mortality rate were independent risk factors for higher in-hospital mortality of V-V ECMO-supported patients(cutoff:1.5％and 7.0％;95％confidence interval:1.05-1.48 and 1.04-1.45;odds ratios:1.25 and 1.23;P=0.012 and P=0.015,respectively).Meanwhile,the V-V ECMO center volume was a protective factor(cutoff of ≥ 50 cases within the 3-year study period;95％confidence interval:0.57-0.83,odds ratio:0.69,P=0.0001).The subgroup analysis of 864 patients in 11 high-volume centers further strengthened these findings.Thus,ICU quality may play an important role in improving the prognosis of V-V ECMO-supported patients.

veno-venous extracorporeal membrane oxygenationin-hospital mortalityhigh-volume centersquality controlintensive care unit capacity parameters

Wei Cheng、Jieqing Chen、Xudong Ma、Jialu Sun、Sifa Gao、Ye Wang、Longxiang Su、Lu Wang、Wei Du、Huaiwu He、Yujie Chen、Zunzhu Li、Qi Li、Jianhua Sun、Hongbo Luo、Jinbang Liu、Guangliang Shan、Bing Du、Yanhong Guo、Dawei Liu、Chang Yin、Xiang Zhou、on behalf of the China National Critical Care Quality Control Center-the ECMO quality improvement ac

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Department of Critical Care Medicine,State Key Laboratory of Complex Severe and Rare Diseases,Peking Union Medical College Hospital,Chinese Academy of Medical Science and Peking Union Medical College,Beijing 100730,China

Information Center Department/Department of Information Management,State Key Laboratory of Complex Severe and Rare Diseases,Peking Union Medical College Hospital,Peking Union Medical College & Chinese Academy of Medical Sciences,Beijing 100730,China

Department of Medical Administration,National Health Commission of the People's Republic of China,Beijing 100044,China

National Institute of Hospital Administration,National Health Commission of the People's Republic of China,Beijing 100044,China

School of Population Medicine and Public Health,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China

Department of Epidemiology and Biostatistics,Institute of Basic Medicine Sciences,Chinese Academy of Medical Sciences(CAMS)&School of Basic Medicine,Peking Union Medical College,Beijing 100730,China

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Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(CIFMS)from the CAMSNational Key Research and Development Program of China,Ministry of Science and Technology of the People's Republic of China北京市自然科学基金CAMS Endowment FundChina Medical Board Open Competition ProgramChinese Medical Information and Big Data Association(CHMIA)Special Fund for Emergency Project

2021-I2M-1-0622021YFC2500801M210192021-CAMS-JZ00420-381

2024

10.1007/s11684-023-1014-x

医学前沿
高等教育出版社

医学前沿

CSTPCD
影响因子：1.362
ISSN：2095-0217
年,卷(期)：2024.18(2)
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