首页|Preparation of chitosan/alginate microcapsules by high-voltage electrostatic method
Preparation of chitosan/alginate microcapsules by high-voltage electrostatic method
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Chitosan and sodium alginate have the opposite charges; they can become a gelatin by the electrostatic attraction, High-voltage electrostatic droplet generator method was used to prepare chitosan-sodium alginate microcapsule. Multi-layer chitosan-sodium aiginate microcapsule was prepared through layer-by-layer self-assembly, and the morphology was investigated.In addition, the release property of ofloxacin in microcapsules was studied by UV-Vis microscopy under different conditions such as pH value, layer number, etc. The results showed that the prepared microcapsules have a smooth surface with average particle size about 100 μm. The result of controlled release indicated that the prepared microcapsules are pH-independent, and the rate of release decreased when the layer number increases.
chitosansodium alginateelectrospraying
Yufei AI、Shuang GUO、Qi ZHANG、Jing QIAO、Xuanyue GAO、Jun NIE、Dongzhi YANG
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State Key Laboratory of Chemical Resource Engineering, Key Laboratory of Beijing City on Preparation and Processing of Novel Polymer Materials, Beijing University of Chemical Technology, Beijing 100029, China
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