中国化学前沿2011,Vol.6Issue(3) :200-205.DOI:10.1007'sl1458-011-0245-6

Photo-affinity labeling strategy to study the binding site of G protein-coupled receptors

Yihui CHEN
中国化学前沿2011,Vol.6Issue(3) :200-205.DOI:10.1007'sl1458-011-0245-6

Photo-affinity labeling strategy to study the binding site of G protein-coupled receptors

Yihui CHEN1
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作者信息

  • 1. Beijing Laviana Pharmatech Co., Ltd., Beijing 102206, China
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Abstract

G protein-coupled receptors (GPCRs) are involved in the control of every aspect of our behavior and physiology.GPCR can be involved in pathological processes as well and are linked to numerous diseases,including cardiovascular and mental disorders,retinal degeneration,cancer,and AIDS.This article reviews the methods of approaching photo-affinity labeling strategy to obtain the possible G protein-coupled receptors's binding site.

Key words

GPCR/photo-affinity/labeling/rhodopsin/transmembrane/structure/binding

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出版年

2011
中国化学前沿
高等教育出版社

中国化学前沿

ISSN:1673-3495
参考文献量59
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