Research progress on the repair of tendon injuries with Tissue Engineering Technology
Tendon injuries are frequently encountered in clinical practice,and traditional repair methods rarely achieve complete restoration of the tendon's original structure and functionality.The challenges of accelerating and optimizing the heal-ing of injured tendons,enhancing the strength of the regenerated tendon,and preventing adhesion remain significant in clinical settings.Tendon tissue engineering,which combines material science,cell biology,and molecular biology,involves the syner-gistic application of multiple factors to create functional constructs and has become an emerging technique with promise for re-pair.The maximization of the regenerative potential of these elements is a critical research question.Future research should concentrate on discovering the optimal combinations of cells,biosignals,and scaffolds to produce tissue that emulates the char-acteristics of an undamaged,natural tendon.This review will cover various aspects,including the fabrication of tendon tissue scaffolds,the selection of seed cells,strategies for the modulation of healing-related biosignals,and provide a summary with prospective insights,aiming to enhance the comprehension of tissue engineering techniques in tendon injury repair and to in-spire innovative applications in this domain.
TendonInjury and repairTissue engineering scaffoldSeed cellsBiosignals
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