Guidelines for the prevention of osteoporosis-related complications following lumbar fusion and internal fixation(2024)
With the aging of the population,an increasing number of patients with lumbar degenerative diseases are complicated with osteoporosis.Patients with osteoporosis are at a higher risk of complications such as internal fixation failure and pseudarthrosis following lumbar fusion and internal fixation,which seriously affects surgical efficacy.Currently,there is a high prevalence of missed screening and misdiagnosis of osteoporosis in this patient population,low rates of pharmacological treatment,and a lack of related diagnosis and treatment guidelines.Although the existing guidelines or consensuses provide important guidance for the diagnosis and treatment of osteoporosis itself,they lack relevant content for patients undergoing lumbar fusion and internal fixation,hindering the prevention of osteoporosis-related surgical complications.Therefore,the Chinese Preventive Medical Association Spine Disease Prevention and Control Professional Committee,in collaboration with the Chinese Rehabilitation Medical Association Osteoporosis Prevention and Rehabilitation Professional Committee,formed an expert group.Following the principles and methods for guideline development,10 key clinical issues were identified.Based on the relevant evidence-based medicine evidence,19 recommendations were finally formed through four rounds of expert discussion using GRADE evidence quality grading method.These guidelines mainly cover the following aspects:accurate preoperative evaluation of bone mineral density and the diagnosis of osteoporosis;the key points for preventing perioperative complications;postoperative osteoporosis medication,patient management,and rehabilitation.It aims to effectively reduce the risk of osteoporosis-related surgical complications in patients undergoing lumbar fusion and internal fixation through a comprehensive"preoperative-intraoperative-postoperative"management strategy.
OsteoporosisLumbar Fusion and Internal FixationLumbar Degenerative DiseasesGuideline