首页|腰椎融合内固定术患者骨质疏松相关并发症预防指南(2024)

腰椎融合内固定术患者骨质疏松相关并发症预防指南(2024)

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随着人口老龄化的加剧,越来越多的腰椎退行性疾病患者合并骨质疏松症.骨质疏松症患者在腰椎融合内固定术后出现内固定失败、假关节形成等并发症的风险更高,严重影响预后.目前,该患者群体骨质疏松症漏筛、漏诊现象较普遍,药物治疗率偏低,且相关诊疗规范尚不完善.已有指南或共识对骨质疏松症本身的诊疗问题提供了重要指导,但缺乏针对腰椎融合内固定术患者群体的相关内容,不利于其骨质疏松相关手术并发症的预防.因此,中华预防医学会脊柱疾病预防与控制专业委员会联合中国康复医学会骨质疏松预防与康复专业委员会组成专家组,遵循指南制定原则和方法,遴选出10个关键临床问题,基于相关循证医学证据,采用GRADE证据质量分级方法,通过4轮专家讨论会,最终形成19条推荐意见.本指南内容主要涉及术前骨密度精准评估与骨质疏松症诊断,术中骨质疏松相关并发症预防要点,术后抗骨质疏松用药、患者管理及康复,旨在通过"术前-术中-术后"的综合管理策略,有效降低腰椎融合内固定术患者骨质疏松相关并发症的发生风险.
Guidelines for the prevention of osteoporosis-related complications following lumbar fusion and internal fixation(2024)
With the aging of the population,an increasing number of patients with lumbar degenerative diseases are complicated with osteoporosis.Patients with osteoporosis are at a higher risk of complications such as internal fixation failure and pseudarthrosis following lumbar fusion and internal fixation,which seriously affects surgical efficacy.Currently,there is a high prevalence of missed screening and misdiagnosis of osteoporosis in this patient population,low rates of pharmacological treatment,and a lack of related diagnosis and treatment guidelines.Although the existing guidelines or consensuses provide important guidance for the diagnosis and treatment of osteoporosis itself,they lack relevant content for patients undergoing lumbar fusion and internal fixation,hindering the prevention of osteoporosis-related surgical complications.Therefore,the Chinese Preventive Medical Association Spine Disease Prevention and Control Professional Committee,in collaboration with the Chinese Rehabilitation Medical Association Osteoporosis Prevention and Rehabilitation Professional Committee,formed an expert group.Following the principles and methods for guideline development,10 key clinical issues were identified.Based on the relevant evidence-based medicine evidence,19 recommendations were finally formed through four rounds of expert discussion using GRADE evidence quality grading method.These guidelines mainly cover the following aspects:accurate preoperative evaluation of bone mineral density and the diagnosis of osteoporosis;the key points for preventing perioperative complications;postoperative osteoporosis medication,patient management,and rehabilitation.It aims to effectively reduce the risk of osteoporosis-related surgical complications in patients undergoing lumbar fusion and internal fixation through a comprehensive"preoperative-intraoperative-postoperative"management strategy.

OsteoporosisLumbar Fusion and Internal FixationLumbar Degenerative DiseasesGuideline

中华预防医学会脊柱疾病预防与控制专业委员会、中国康复医学会骨质疏松预防与康复专业委员会、李危石

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骨质疏松 腰椎融合内固定术 腰椎退行性疾病 指南

国家重点研发计划

2023YFC3604400

2024

中华骨与关节外科杂志
中国医学科学院 中国协和医学院

中华骨与关节外科杂志

CSTPCD北大核心
影响因子:0.906
ISSN:2095-9958
年,卷(期):2024.17(5)
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