首页|单侧双通道脊柱内镜手术治疗腰椎退行性疾病围手术期隐性失血的危险因素分析

单侧双通道脊柱内镜手术治疗腰椎退行性疾病围手术期隐性失血的危险因素分析

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目的:分析单侧双通道内镜(UBE)手术治疗腰椎退行性疾病围手术期隐性失血的危险因素.方法:回顾性分析2020年12月至2022年12月于首都医科大学附属北京友谊医院接受UBE手术治疗的81例单节段腰椎退行性疾病患者的临床资料.其中人口统计学资料包括性别、年龄、身高、体重、体重指数(BMI)、病史、吸烟史、饮酒史;实验室检查资料包括术前与术后第1日血红蛋白(Hb)、白蛋白(Alb)、红细胞压积(HCT)、血小板计数及术前凝血功能指标、术前生化指标;影像学资料包括目标节段皮下软组织厚度、皮下脂肪厚度、椎旁肌肉厚度、椎旁肌肉厚度与皮下软组织厚度比;手术资料包括诊断、美国麻醉医师协会(ASA)分级、手术时间、手术节段、是否行椎间盘切除、单侧/双侧减压、术中出血量、术后第1日引流量.计算围手术期总失血量及隐性失血量,采用单因素分析和Spearman相关分析探讨UBE手术隐性失血的相关危险因素,应用多元线性回归分析进一步分析影响UBE手术隐性失血的独立危险因素.结果:本组患者总失血量为516.5(453.1,598.8)mL,显性失血量为58.0(40.1,72.3)mL,隐性失血量为342.6(285.6,412.4)mL.单因素分析结果显示,性别、是否行椎间盘切除与UBE手术围手术期隐性失血有关联(P均<0.05);相关分析结果显示,身高、手术时间、术前HCT及Hb、Alb、D-二聚体、甘油三脂(TG)、总胆固醇(TC)、低密度脂蛋白(LDL)水平与UBE手术围手术期隐性失血有相关性(P均<0.05).进一步多元线性回归分析结果显示,术前Alb水平、椎间盘切除和手术时间是UBE手术围手术期隐性失血的独立危险因素(P均<0.05).结论:UBE手术治疗腰椎退行性疾病围手术期存在明显的隐性失血.术前Alb水平、椎间盘切除和手术时间可能是UBE手术围手术期隐性失血的独立危险因素.
Risk factors for hidden blood loss in unilateral biportal endoscopic spinal surgery for lumbar degenerative diseases
Objective:To identify the risk factors for hidden blood loss(HBL)in patients with single-segment lumbar degenerative diseases who have undergone unilateral biportal endoscopic(UBE)spinal surgery.Methods:A retrospective analysis was conducted on the clinical data of 81 patients with single-segment lumbar degenerative disease who underwent UBE surgery at Beijing Friendship Hospital,Capital Medical University from November 2020 to December 2022.The demographic data included sex,age,height,weight,body mass index(BMI),medical history,smoking and drinking history.The laboratory examination data included pre-and post-operative hemoglobin(Hb),albumin(Alb),hematocrit(HCT),platelet count,preoperative coagulation function,and preoperative biochemical indicators.Imaging data included the thickness of subcutaneous soft tissue,subcutaneous fat,paraspinal muscle thickness,and the ratio of paraspinal muscle thickness to subcutaneous soft tissue thickness at the target segment.Surgical data included diagnosis,American Society of Anesthesiologists classification,operation duration,surgical segment,discectomy,decompression count,intraoperative blood loss,and first-day postoperative drainage.The total perioperative blood loss and HBL were calculated.Univariate and correlation analyses were performed to explore risk factors for HBL during UBE surgery,and multivariate linear regression analysis was used to further identify the independent risk factors.Results:The total perioperative blood loss was 516.5(453.1,598.8)mL,with a visible blood loss of 58.0(40.1,72.3)mL and a HBL of 342.6(285.6,412.4)mL.Univariate analysis indicated that sex,height,history of hypertension,preoperative Hb,HCT and Alb,triglyceride,total cholesterol,and low-density lipoprotein levels were associated with HBL during UBE surgery.Correlation analysis revealed that discectomy and operation duration were correlated with HBL during UBE surgery(all P<0.05).Multiple linear regression analysis confirmed that the preoperative Alb level,discectomy and operation duration were independent risk factors for HBL during UBE surgery(all P<0.05).Conclusions:UBE surgery for single-segment lumbar degenerative diseases has significant HBL during the perioperative period.Preoperative Alb level,discectomy and operation duration may be independent risk factors for HBL.

Unilateral Biportal EndoscopyLumbar Degenerative DiseasesHidden Blood LossRisk Factor

林吉生、吕芳硕、李锦军、费琦

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首都医科大学附属北京友谊医院骨科,北京 100050

单侧双通道内镜手术 腰椎退行性疾病 隐性失血 危险因素

通州区科技计划项目

KJ2024CX053

2024

中华骨与关节外科杂志
中国医学科学院 中国协和医学院

中华骨与关节外科杂志

CSTPCD北大核心
影响因子:0.906
ISSN:2095-9958
年,卷(期):2024.17(9)