Factors affecting ligamentum nuchae calcification in patients with cervical spondylosis
Objective:To investigate the relationships between the occurrence of ligamentum nuchae calcification in patients with cervical spondylosis and changes in the cervical intervertebral disc height and cervical imaging parameters.Methods:A retrospective analysis was conducted on the clinical data of 124 patients diagnosed with cervical spondylosis at the Second Affiliated Hospital of Wannan Medical College from June 2020 to June 2023.All patients underwent cervical anteroposterior and lateral X-ray and CT examinations.Patients were divided into a calcification group(83 cases)and a non-calcification group(41 cases)based on the presence of ligamentum nuchae calcification.The cervical intervertebral disc height of each segment,local Cobb angle,cervical curvature classification,Jackson stress curve,and clinical symptoms were compared between two groups to identify the risk factors for ligamentum nuchae calcification.Results:Patients in the calcification group were significantly older and had longer disease durations than those in the non-calcification group(both P<0.05).The intervertebral disc heights at C4-5 and C5-6 in the calcification group were significantly lower than those in the non-calcification group(both P<0.05).The local Cobb angles at C4-5 and C5-6 in the calcification group were also significantly smaller than those in the non-calcification group(both P<0.05).The proportion of patients with straight cervical curvature and VAS scores in the calcification group were significantly higher than those in the non-calcification group,while the Jackson stress curve was significantly lower than that in the non-calcification group(all P<0.05).Logistic regression analysis revealed that older age,longer disease duration,straight cervical curvature,higher VAS score,and decreased intervertebral disc height at C4-5 and C5-6 were independent risk factors for ligamentum nuchae calcification in patients with cervical spondylosis(all P<0.05).Conclusions:Decreased intervertebral disc height at C4-5 and C5-6 and straight cervical curvature increase the risk of ligamentum nuchae calcification in patients with cervical spondylosis.Correcting the intervertebral disc height and cervical curvature can help reduce the risk of ligamentum nuchae calcification.