首页|骨质疏松性椎体压缩骨折经皮椎体后凸成形术与经皮椎体成形术中骨水泥弥散高度对手术效果的影响

骨质疏松性椎体压缩骨折经皮椎体后凸成形术与经皮椎体成形术中骨水泥弥散高度对手术效果的影响

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目的:探究骨质疏松性椎体压缩骨折(OVCF)经皮椎体后凸成形术(PKP)与经皮椎体成形术(PVP)中骨水泥弥散高度对手术效果的影响.方法:回顾性分析2023年5月至2024年3月首都医科大学附属北京世纪坛医院收治的115例骨质疏松性T11~L2椎体压缩骨折患者的临床资料,并根据手术方式不同分为PKP组60例和PVP组55例,比较两组患者术前及术后疼痛视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)、伤椎后凸Cobb角、术后骨水泥渗漏发生率、邻近椎体骨折发生率、术后伤椎骨水泥弥散高度及其占比情况.结果:所有患者均顺利完成手术,与PVP组比较,PKP组患者手术时间更长、术中透视次数更多、骨水泥注入量更多(P均<0.05).两组患者术后1 d、术后3个月VAS评分均较术前明显降低(P均<0.05),但组间比较差异均无统计学意义(P均>0.05).两组患者术后6个月ODI、伤椎后凸Cobb角均较术前明显降低(P均<0.05),且PKP组患者均明显优于PVP组(P均<0.05).PKP组患者术后骨水泥渗漏发生率为3.33%(2/60),显著低于PVP组14.44%(8/55),差异有统计学意义(P<0.05).PKP组患者术后邻近椎体骨折发生率为5.00%(3/60),略低于PVP组的10.91%(6/55),差异无统计学意义(P>0.05).PKP组患者椎体前柱高度和椎体前柱骨水泥弥散高度、椎体中柱高度和椎体中柱骨水泥弥散高度、椎体高度和椎体骨水泥最大弥散高度均明显高于PVP组,差异均有统计学意义(P均<0.05).PVP组与PKP组患者椎体前柱骨水泥弥散高度占比(r=-0.721,P<0.05;r=-0.703,P<0.05)和椎体骨水泥最大弥散高度占比(r=-0.584,P<0.05;r=-0.467,P<0.05)均与术后6个月ODI呈显著负相关,而椎体中柱骨水泥弥散高度占比(r=-0.088,P>0.05;r=-0.023,P>0.05)与术后6个月ODI之间无显著相关性.结论:PKP与PVP均可显著缓解OVCF患者的疼痛,并减轻其功能活动障碍.PVP的优势在于手术时间较短,术中透视次数较少,骨水泥注入量较少;PKP的优势在于椎体高度恢复效果更佳,术后骨水泥渗漏风险较低,疼痛缓解及功能障碍恢复程度更好.骨水泥弥散高度及其在椎体高度中占比可作为预估PVP和PKP手术效果的参考指标.
Effect of bone cement dispersion height in percutaneous kyphoplasty and percutaneous vertebroplasty on the surgical outcomes for osteoporotic vertebral compression fractures
Objective:To explore the effect of bone cement dispersion height on the surgical efficacy of percutaneous kyphoplasty (PKP) and percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fracture (OVCF). Methods:The clinical data of 115 patients with osteoporotic T11-L2 spinal fractures admitted to Beijing Shijitan Hospital Affiliated to Capital Medical University from May 2023 to March 2024,were retrospectively analyzed. Patients were divided into the PKP group (n=60) and the PVP group (n=55) according to surgical method. The preoperative and postoperative visual analog scale (VAS) scores,Oswestry Disability Index (ODI),kyphosis angle (Cobb angle),postoperative bone cement leakage,and the incidence of adjacent vertebral fractures were analyzed between the two groups. The postoperative bone cement dispersion height and its proportion in vertebral body were also compared between the two groups. Results:All patients successfully underwent surgery. Compared with the PVP group,the PKP group had significantly longer surgery times,more intraoperative fluoroscopy sessions,and more bone cement usage (all P<0.05). The VAS scores of both groups decreased significantly at 1 day and 3 months postoperatively compared to preoperative levels (all P<0.05),with the PKP group showing significantly lower VAS scores than the PVP group at both time points (all P<0.05). The ODI scores of both groups were significantly reduced at 6 months postoperatively compared to preoperative levels (all P<0.05),with the PKP group exhibiting significantly lower ODI scores than the PVP group (P<0.05). The incidence of postoperative bone cement leakage in the PKP group was 3.33% (2/60),which was significantly lower than that in the PVP group (14.44%,8/55) (P<0.05). The incidence of adjacent vertebral fractures after surgery in the PKP group was 5.00% (3/60),which was slightly lower than that in the PVP group (10.91%,6/55) (P>0.05). The PKP group had significantly higher anterior column height,bone cement height of the anterior column,middle column height,bone cement height of the middle column,vertebral body height,and maximum bone cement height than those in the PVP group (all P<0.05). The proportion of bone cement dispersion height of anterior column (r=-0.721,P<0.05;r=-0.703,P<0.05) and the maximum bone cement dispersion height (r=-0.584,P<0.05;r=-0.467,P<0.05) were significantly negatively correlated with ODI score at 6 months postoperatively in both groups,while the proportion of bone cement dispersion height of the middle column showed no significant correlation with ODI score at 6 months postoperatively (r=-0.088,P>0.05;r=-0.023,P>0.05). Conclusions:Both PKP and PVP can significantly improve pain symptoms and alleviate functional impairment in OVCF patients. The advantages of PVP include a shorter surgery time,fewer intraoperative fluoroscopy sessions,and a less bone cement usage. The advantages of PKP include better recovery of vertebral height a lower risk of postoperative bone cement leakage,and better recovery in pain and functional impairment. The bone cement dispersion height and its proportion in the vertebral body can serve as reference indicators for predicting the surgical outcomes of PVP and PKP.

Osteoporotic Vertebral Compression FracturesPercutaneous KyphoplastyPercutaneous Vertebroplasty

李尔楠、丁立祥、付胜良、姚明涛、杨磊

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首都医科大学附属北京世纪坛医院脊柱外科,北京 100038

骨质疏松性椎体压缩骨折 经皮椎体后凸成形术 经皮椎体成形术

2024

中华骨与关节外科杂志
中国医学科学院 中国协和医学院

中华骨与关节外科杂志

CSTPCD北大核心
影响因子:0.906
ISSN:2095-9958
年,卷(期):2024.17(12)