Incidence and risk factors of deep venous thrombosis following single-dose anticoagulants combined with lower limb functional exercises after revision total hip arthroplasty
Objective:To investigate the incidence and risk factors of deep venous thrombosis (DVT) following single-dose anticoagulants combined with lower limb functional exercises after revision total hip arthroplasty (THA). Methods:A retrospective analysis was conducted on the clinical data of 199 patients who underwent revision THA at the First Affiliated Hospital of Xinjiang Medical University from June 2018 to June 2022. The included patients received single-dose anticoagulants combined with lower limb functional exercises to prevent DVT and were divided into two groups based on the occurrence of DVT postoperatively:the DVT group (46 cases) and the non-DVT group (153 cases). The distributions of DVT location,number of involved venous branches,and progression to pulmonary embolism (PE) were statistically analyzed. Univariate analysis was used to compare the differences in various indicators between the two groups,and multivariate analysis was conducted to explore the independent risk factors for DVT. Results:The incidence of postoperative proximal DVT was 3.5％,while distal DVT was 19.6％. The main veins affected by DVT were,in order,the calf muscular vein,posterior tibial vein,peroneal vein,popliteal vein,deep femoral vein,superficial femoral vein,and external iliac vein. Proximal DVT mainly involved four veins,while distal DVT affected a single vein. The risk factor analysis showed that cardiovascular disease (OR=2.214,95％CI=1.028-4.769;P<0.05),revision THA (OR=4.311,95％CI=1.199-15.502;P<0.05),and three-component revision arthroplasty (OR=4.280,95％CI=1.096-16.722;P<0.05) were independent risk factors for the occurrence of DVT. Conclusions:The use of single-dose anticoagulants combined with lower limb functional exercises after revision THA to prevent DVT is feasible. Under this anticoagulation regimen,the incidence of calf muscular venous thrombosis is the highest. Cardiovascular disease,revision THA,and three-component revision arthroplasty were identified as independent risk factors for DVT after revision THA.
Revision Total Hip ArthroplastyDeep Venous ThrombosisSingle-doseAnticoagulationFunctional Exercise
万方数据
维普
