Mechanism of the bone morphogenetic protein pathway in the bone metastasis of prostate carcinoma
Bone morphogenetic protein (BMP) are a class of growth factors that regulate cellular functions and are essential for processes such as embryonic development,tissue and organ differentiation,and bone formation. The BMP pathway has been proven to be closely related to the occurrence of tumors. Prostate carcinoma (PC) is one of the common malignant tumors in men worldwide,and bone metastasis is common in advanced PC. Once bone-related events occur,patients' quality of life and prognosis can severely be affected. Currently,the regulatory mechanisms of the occurrence and progression of PC bone metastasis remain unclear. This article summarizes the mechanisms of the BMP pathway in the process of PC bone metastasis,providing a theoretical basis and reference for the early diagnosis and targeted treatment of PC bone metastasis.
Bone Morphogenetic ProteinBone Morphogenetic Protein PathwayProstate CarcinomaBone Metastasis
万方数据
维普
