Objective To explore the influencing factor on thyroid disease among radiation workers.Methods The health examination data of 2 529 radiation workers were collected,analyze their thyroid function laboratory indexes and thyroid ultrasound examination results.Results The results showed that women,older individual and radiological workers engaged in diagnostic radiology and related jobs had a higher risk of developing autoimmune thyroiditis(especially those people whose service time were≥20 years)and thyroid nodules;and the risk of developing thyroid dysfunction after suffering from autoimmune thyroiditis was twice that of not suffering from thyroiditis(P<0.05);furthermore,the multivariate Logistic regression analysis showed that there was no correlation between radiation exposure and thyroid nodules.Conclusion The results suggested that the condition of thy-roid disease among radiation was not optimistic,the radiation staff should raise their awareness of occupational protection,and the occupational protection measures for them should be.