Objective To compare the result of dual-energy X-ray absorptiometry(DXA)for the diagnosis of osteoporosis by the detection of mid-axial and peripheral bone density,and to study the relationship between DXA measurements of bone density at different sites and its changes with age.Methods 518 patients aged 50-89 with an average age of(67.8±8.8)years were collected from the Osteoporosis Department of the Affiliated Hospital of Xuzhou Medical University from December 2020 to February 2022.Divided the subjects into 4 groups based on age,measured the T-scores of axial bone density and peripheral bone density using DXA,compared the differences between the two in diagnosing osteoporosis,and conducted consistency tests.Recorded the DXA T-scores of Lumbar 1-4,total hip,and femoral neck in each group,and observed the characteristics of bone density changes in each area with age.Results The difference between mid-axial DXA and peripheral DXA in the diagnosis of osteoporosis was statistically significant(x2=188.65,P＜0.05),and the concordance between the two tests was statistically significant,with a weak concordance(Kappa=0.2,P＜0.05).There were differences in T-scores between sites of mid-axial BMD and different trends with age.Conclusion The combination of mid-axial BMD with peripheral BMD can improve the detection rate of osteoporosis,and BMD T-scores between different parts of the mid-axial bone cannot be substituted for each other.
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