The pathogenesis,diagnosis,and treatment of glucocorticoid-induced osteoporosis were analyzed under the guidance of the"phase fire theory".It was concluded that excessive hormone levels damage the body,leading to wild movement of phase fire and result ing in an imbalance of Yin and Yang,dysfunction of marrow osteogenesis,and the development of GIOP.The fundamental pathogenesis of GIOP is related to the overreaction of fire.Treatment should be based on regulating the phase fire,adjusting Yin and Yang as a framework,strengthening water as the main focus,nourishing Yin and replenishing essence,supplementing Zuo-Gui Pills or returning phase fire to reduce excess fire energy,while warming Yang energy and supplementing Jin-Gui-Shen-Qi Pills.Differentiating and treating GIOP based on the theory of"phase fire"has unique practical value and deserves further discussion in order to provide new insights for clinical prevention and treatment of GIOP.
关键词
相火理论/糖皮质激素性骨质疏松/中医药/病机/治法
Key words
phase-fire theory/glucocorticoid-induced osteoporosis/traditional chinese medicine/pathogenesis/treatment