3种量表预测肾病综合征患者发生静脉血栓栓塞症的效能比较
Comparison of the efficacy of three scales in predicting Venous Thromboembolism in patients with Nephrotic Syndrome
姜楠 1刁佳 1苏春燕 1崔专1
作者信息
- 1. 北京大学第三医院肾内科,100191 北京市
- 折叠
摘要
目的:比较Pauda、Caprini、Autar 3 种血栓风险评估量表对肾病综合征患者发生静脉血栓栓塞症的风险预测效能,为临床提供参考.方法:便利选取 2018 年1月至 2023 年3月于北京市某三级甲等医院肾内科就诊的 287例肾病综合征住院患者为研究对象,将确诊为静脉血栓栓塞症的51例患者纳入血栓组,未发生静脉栓塞症的 236 例患者为非血栓组,分别采用3 种风险评估量表对患者进行评分,绘制受试者工作特征曲线进行预测效能对比.结果:Pauda、Caprini、Autar量表的最佳诊断界值分别为 0.5、3.5、5.5,受试者工作特征曲线下面积分别为 0.613、0.701、0.623.结论:3 种量表均可在一定程度上预测肾病综合征患者发生静脉血栓栓塞症的风险,预测能力从高到低依次为Caprini、Autar、Pauda量表.
Abstract
Objective:To compare the predictive effects of Pauda,Caprini,and Autar thrombus risk assessment scales on the risk of Venous Thromboembolism(VTE)in patients with Nephrotic Syndrome.Methods:A total of 287 hospitalized patients diagnosed with Nephrotic Syndrome in the Department of Nephrology at a tertiary grade A hospital in Beijing from January 2018 to March 2023 were recruited.A total of 51 patients diagnosed with VTE,and 236 patients without VTE(non-VTE group).Three risk assessment scales were used to assess the thrombus risk,and Receiver Operation Characteristic(ROC)curves were drawn for comparative prediction.Results:The optimal diagnostic thresholds for the Pauda,Caprini,and Autar scales were 0.5 points,3.5 points,and 5.5 points,respectively.The area under the ROC Curve(AUC)was 0.613,0.701,and 0.623,respectively.Conclusion:All three scales can predict the risk of VTE in Nephrotic Syndrome to a certain extent,with the Caprini,Autar,and Pauda scales ranking in order of predictive ability from high to low.
关键词
肾病综合征/血栓风险评估/Pauda量表/Caprini量表/Autar量表/效能Key words
Nephrotic Syndrome/thrombosis risk assessment/Pauda Scale/Caprini Scale/Autar Scale/efficacy引用本文复制引用
基金项目
北京大学第三医院护理科研种子基金(BYSYHL2020002)
出版年
2024
NETL
NSTL
万方数据