ICU患者暴露性角膜病变发生率及危险因素的Meta分析
Incidence and risk factors of exposure keratopathy in ICU patients:a Meta-analysis
黄光梅 1权明桃 2苟雅婷 1吴林松 1钟燕强1
作者信息
- 1. 遵义医科大学附属医院重症医学科二病区,563000 贵州省遵义市
- 2. 遵义医科大学附属医院护理部,563000 贵州省遵义市
- 折叠
摘要
目的:系统分析ICU患者暴露性角膜病变的发生率及危险因素,为临床医护人员进行早期干预提供参考依据.方法:计算机检索国内外数据库中关于ICU患者暴露性角膜病变发生率和(或)危险因素的文献,严格按照纳入与排除标准筛选文献,应用Stata 17.0 软件进行Meta分析.用Begg检验和漏斗图判定发表偏倚.结果:共纳入15篇文献,涉及 2 470 例患者,ICU患者暴露性角膜病变合并发生率为30.0%,眼睑闭合不全、结膜水肿、凸眼、机械通气及格拉斯哥评分<9 分是ICU患者暴露性角膜病变的危险因素(P<0.05).结论:暴露性角膜病变在ICU患者中发生率较高,临床医护人员应根据相关危险因素进行早期有针对性的干预,降低其发生率.
Abstract
Objective:To systematically analyze the incidence and risk factors of exposure keratopathy in ICU patients,provide reference basis for early intervention by clinical medical staff.Methods:We searched literature on the incidence and(or)risk factors of exposure keratopathy in ICU patients from domestic and foreign databases.The literature were screened strictly according to the inclusion and exclusion criteria,and Meta-analysis was performed using Stata 17.0 software.Publication bias were determined by the Beggs test and the funnel plot.Results:A total of 15 articles involving 2470 patients were included,and the incidence of exposure keratopathy in ICU patients was 30.0%.Incomplete eyelid closure,conjunctival edema,convexity of the eye,mechanical ventilation,and the GCS score<9 were the risk factors for exposure keratopathy in ICU patients(all P<0.05).Conclusion:The incidence of exposure keratopathy in ICU patients is relatively high,and the clinical medical staff should conduct targeted intervention early according to the above risk factors to reduce its incidence.
关键词
重症监护病房/暴露性角膜病变/发生率/危险因素/Meta分析Key words
ICU/exposure keratopathy/incidence/risk factors/Meta-analysis引用本文复制引用
基金项目
贵州省科技计划项目(黔科合成果-LC[2024]039)
遵义市科技计划项目(遵市科合HZ字[2021]154号)
出版年
2024