Incidence and risk factors of exposure keratopathy in ICU patients:a Meta-analysis
Objective:To systematically analyze the incidence and risk factors of exposure keratopathy in ICU patients,provide reference basis for early intervention by clinical medical staff.Methods:We searched literature on the incidence and(or)risk factors of exposure keratopathy in ICU patients from domestic and foreign databases.The literature were screened strictly according to the inclusion and exclusion criteria,and Meta-analysis was performed using Stata 17.0 software.Publication bias were determined by the Beggs test and the funnel plot.Results:A total of 15 articles involving 2470 patients were included,and the incidence of exposure keratopathy in ICU patients was 30.0%.Incomplete eyelid closure,conjunctival edema,convexity of the eye,mechanical ventilation,and the GCS score<9 were the risk factors for exposure keratopathy in ICU patients(all P<0.05).Conclusion:The incidence of exposure keratopathy in ICU patients is relatively high,and the clinical medical staff should conduct targeted intervention early according to the above risk factors to reduce its incidence.
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