摘要
目的:遴选并总结肝移植术后代谢综合征患者运动干预的证据,为临床实践提供参考.方法:按照循证资源的"6S"模型,检索临床决策系统、循证数据库、指南网站、综合数据库等共 23 个,检索时限为建库至2023 年10月31日,检索关于肝移植患者代谢综合征运动干预的指南、证据总结、临床决策、专家共识、系统评价.由4 名研究者进行文献质量评价和证据提取、预分级.结果:共纳入16篇文献,其中1篇临床决策、5篇指南、7 篇系统评价、3篇专家共识.从肝移植术后代谢综合征患者运动方案的制定、实施、运动干预的安全管理、患者运动依从性管理、运动干预效果评价 5 个方面形成了27条证据.结论:本研究结果可为临床医护人员实施肝移植患者代谢综合征的运动干预提供循证依据.
Abstract
Objective:To collect and summarize the evidence on exercise interventions for adult patients with metabolic syndrome after liver transplantation to providing a reference for clinical practice.Methods:According to the"6S"model of evidence-based retrieval,a top-down search was conducted across 23 databases from inception of database to 31 Oct,2023,including clinical decision systems,evidence-based databases,guideline websites,and comprehensive databases.This search focused on guidelines,evidence summaries,clinical decision,expert consensus,and systematic reviews related to exercise interventions for liver transplant patients with metabolic syndrome.Four researchers were responsible for the literature quality assessment,evidence extraction,and preliminary grading.Results:A total of 16 publications were included,comprising 1 clinical decision,5 guidelines,7 systematic reviews,and 3 expert consensuses.Finally 27 evidence recommendations were formed,covering the development,implementation,safety management,compliance management,and evaluation of intervention effects of exercise programs for patients with metabolic syndrome after liver transplantation.Conclusion:The results of this study can assist clinical medical staff in implementing exercise interventions for liver transplant patients with metabolic syndrome,providing an evidence-based foundation.
基金项目
2024年度浙江省中医药科技计划(2024ZL845)
2024年度浙江省中医药科技计划(2024ZL846)