Development and test of reliability and validity of MD Anderson Symptom Inventory-Acute Leukemia Module
Objective:To develop MD Anderson Symptom Inventory-Acute Leukemia Module and assess its reliability and validity.Methods:A preliminary scale was developed through literature review,semi-structured interviews,Delphi expert consultation,and patient pre-surveys.A clinical investigation involving 235 adult patients with Acute Leukemia was conducted to assess its reliability and validity.Results:MD Anderson Symptom Inventory-Acute Leukemia Module consists of 25 items,including 19 symptom items and 6 items assessing the interference of symptoms with daily life.The content validity results indicate that both the I-CVI and S-CVI are greater than 0.8.The results of confirmatory factor analysis showed that the revised model suitability indexes were χ2/df=2.230,RMSEA=0.072,GFI=0.976,CFI=0.955,IFI=0.956,NFI=0.923,TLI=0.915.The Cronbach's α coefficient for the total MD Anderson Symptom Inventory-Acute Leukemia Module is 0.941,while the Cronbach's α coefficient for the Acute Leukemia Module is 0.707.Conclusion:MD Anderson Symptom Inventory-Acute Leukemia Module developed in this study has demonstrated good reliability,and validity.It is an accurate and objective tool for assessing symptoms of Acute Leukemia patients.
Acute LeukemiaMD Anderson Symptom Inventorysymptomassessment toolsreliabilityvalidity
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