摘要
目的:对比分析干预前后我院Ⅰ类切口使用抗菌药物情况。方法选取2012年1~12月Ⅰ类切口出院病历186份作为干预前组;从2013年9月起开始进行药学干预,2014年1~12月Ⅰ类切口出院病历194例作为干预后组,对比两组抗菌药物使用率及24h内停用率、同期全院Ⅰ类切口感染情况。结果干预前抗菌药物使用率(66.00%)、24h内停用率(43.00%)与干预后比较明显较高(39.18%、26.32%),差异有统计学意义(P<0.05)。干预后同期全院Ⅰ类切口感染率与干预前比较差异无统计学意义(P>0.05)。结论通过对Ⅰ类切口抗菌药物使用情况进行干预,有效降低了Ⅰ类切口抗菌药物使用率及24h内停用率,且不增加切口感染率,避免抗菌药物的滥用,对临床合理使用抗菌药物起到了积极的作用。
Abstract
Objective To compare the use of antimicrobial drugs situation of Class I cut in our hospital before and after the intervention. Methods 186 cases of Class I cut in our hospital selected from Jan to Dec in 2012 were regarded as post-intervention group. Patients began to receive pharmaceutical intervention in Sep 2013 , Class I cut discharge records 194 cases were selected from Jan to Dec in 2014 and considered as post-intervention group. The antibiotics use and 24 hours discontinua-tion rates, Class I cut infection in the hospital at the same time of two groups were compared. Results The antibiotics use and 24 hours discontinuation rates (66.00%,43.00%) of pre-intervention group were significantly higher than post-intervention group(39.18%, 26.32%), the difference was statistically significant (P<0.05). Class I cut infection rate between the two groups had no significant difference (P>0.05). Conclusion The antimicrobial drug use intervention of Class I cut effectively reduces the Class I cut antibiotics use and 24 hours discontinuation rates and Class I cut infection rate donˊt increase , the abuse of an-tibiotics can be avoided. It plays a positive role in the clinical rational use of antibiotics.