首页|体素内不相干运动弥散加权成像在儿童腹部良恶性肿瘤诊断中的应用价值

体素内不相干运动弥散加权成像在儿童腹部良恶性肿瘤诊断中的应用价值

扫码查看
目的 分析体素内不相干运动弥散加权成像(IVIM-DWI)在儿童腹部良恶性肿瘤诊断中的应用价值。方法 选取 2020 年 1 月~2022 年 12 月我院收治的 110 例腹部肿瘤患儿为研究对象,其中良性肿瘤 42 例,恶性肿瘤68 例,所有患儿均接受腹部 MRI 平扫、多弥散敏感系数(b)值IVIM-DWI扫描,分析腹部良恶性肿瘤的IVIM-DWI参数,并对参数敏感度、诊断界值、特异度等进行分析。结果 42 例良性肿瘤患者中良性成熟畸胎瘤 20 例,肝血管瘤 10例,节细胞神经瘤 8 例,肝脏局灶性结节增生 4 例。68 例恶性肿瘤患者中神经母细胞瘤 30 例,肝母细胞瘤 14 例,肾母细胞瘤 10 例,淋巴瘤 8 例,未成熟畸胎瘤、横纹肌肉瘤、肾透明细胞肉瘤各 2 例;良性肿瘤与恶性肿瘤患儿f值比较,差异无统计学意义(P>0。05),良性组患儿表观弥散系数(ADC)、真实弥散系数(D)值高于恶性组(P<0。05),灌注相关弥散系数(D*)值低于恶性组(P<0。05);受试者工作特征(ROC)曲线分析结果显示,ADC值诊断良恶性肿瘤的ROC曲线下面积(AUC)、特异度和准确率明显高于D、D*值。结论 在儿童腹部实体肿瘤良恶性鉴别的IVIM-DWI参数中,ADC值的AUC、特异度和准确率较高,可以作为小儿腹部实体肿瘤良恶性鉴别的重要参考依据。
Application value of intravoxel incoherent motion-diffusion weighted imaging in the diagnosis of abdominal benign and malignant tumors in children
Objective To analyze the application of intravoxel incoherent motion-diffusion weighted imaging(IVIM-DWI)in the diagnosis of abdominal benign and malignant tumors in children.Methods 110 children with abdominal tumors admitted to our hospital from Jan 2020 to Dec 2022 were selected,including 42 cases of benign tumors and 68 cases of malignant tumors.All children underwent abdominal MRI plain scan and multi b-value IVIM-DWI scan,the differential IVIM-DWI parameters between benign and malignant abdominal tumors were analyzed,and the sensitivity,diagnostic threshold and specificity of the parameters were analyzed.Results 42 patients with benign tumor were including 20 cases of benign mature teratoma,10 cases of hepatic hemangioma,8 cases of ganglioneuroma,and 4 cases of focal nodular hyperplasia of the liver.68 patients with malignant tumor were including 30 cases of neuroblastoma,14 cases of hepatoblastoma,10 cases of nephroblastoma,8 cases of lymphoma,2 cases of immature teratoma,2 cases of rhabdomyosarcoma,and 2 cases of renal clear cell sarcoma.There was no significant difference in the f value between benign and malignant tumors in children(P>0.05).The ADC and D values were higher in the benign group than that in the malignant group(P<0.05),while the D* value was lower in the benign group than that in the malignant group(P<0.05).ROC analysis showed that the AUC,the specificity and the accuracy rate of ADC were significantly higher than that of D and D*.Conclusion The ADC value,with a high AUC,specificity,and accuracy rate,serves as a crucial reference criterion for distinguishing benign and malignant abdominal tumors in children using IVIM-DWI parameters.

Intravoxel incoherent motionDiffusion weighted imagingChildrenAbdominal benign and malignant tumors

崔鹏翔、杨凯华、周绮

展开 >

郑州大学附属儿童医院 河南省儿童医院 郑州儿童医院医学影像科,河南 郑州 450007

体素内不相干运动 弥散加权成像 儿童 腹部良恶性肿瘤

2024

中国现代医药杂志
北京航天总医院

中国现代医药杂志

影响因子:0.689
ISSN:1672-9463
年,卷(期):2024.26(1)
  • 12