Correlation of serum ferritin and nutritional status with recurrence of healthy hip fracture in patients with intertrochanteric fracture
Objective To investigate the correlation of serum ferritin and nutritional status with recurrence of healthy hip fracture in patients with intertrochanteric fracture.Methods A retrospective analysis was performed on 105 patients with intertrochanteric fracture admitted to our hospital from Jan 2020 to Dec 2022.Patients were divided into recurrent group(45 cases)and non-recurrent group(60 cases)according to whether they had recurrent hip fractures on the healthy side.General data of patients and clinical data such as serum ferritin level and nutritional index were analyzed,and their correlation with recurrence of hip fracture on the healthy side of intertrochanteric fracture were analyzed.Results There were no significant difference in gender and primary operation method between the recurrent group and the non-recurrent group(P>0.05).The age of the recurrent group was higher than that of the non-recurrent group,the BMI of the recurrent group was lower than that of the non-recurrent group,the bone mineral density of the T value was lower than that of the non-recurrent group,the proportion of patients with medical diseases was higher than that of the non-recurrent group,and the Harris score at the last follow-up was lower than that of the non-recurrent group(P<0.05).The serum ferritin level in the recurrent group was higher than that in the non-recurrent group,and the related nutritional indexes detection values(total protein,albumin,prealbumin,transferrin,hemoglobin,lymphocyte count,and MNA-SF score)were lower than those in the non-recurrent group(P<0.05).The nutritional status of the recurrent group was worse than that of the non-recurrent group(P<0.05).The serum ferritin level was negatively correlated with bone mineral density of the T value(r=-0.720,P<0.001),and MNA-SF score was positively correlated with bone mineral density of the T value(r=0.769,P<0.001).Age(OR=1.118),bone mineral density(OR=4.529),serum ferritin level(OR=1.108)and combined medical disease(OR=5.423)were independent risk factors for recurrence of healthy hip fracture in patients with intertrochanteric fracture(P<0.05).BMI(OR=0.696),MNA-SF score(OR=0.071)and Harris score(OR=0.668)at last follow-up were protective factors for recurrence of healthy hip fracture in patients with intertrochanteric fracture(P<0.05).Conclusion Elevaed serum ferritin levels are associated with poorer nutritional status and increased risk of health hip fracture recurrence in intertrochanteric fracture patients.Age,bone mineral density,serum ferritin level and medical comorbidities are independent risk factors for recurrence,while higher BMI,MNA-SF score,and Harris score at the last follow-up confer protective effects.
Intertrochanteric fractureRecurrence of healthy hip fractureSerum ferritinNutritional statusBone mineral density
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