首页|Reactivity-based One-pot Synthesis of Immunosuppressive Glycolipids from the Caribbean Sponge Plakortis simplex

Reactivity-based One-pot Synthesis of Immunosuppressive Glycolipids from the Caribbean Sponge Plakortis simplex

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The first synthesis of three natural glycolipid simplexides 1a-1c, which were isolated from the marine sponge Plakortis simplex and claimed to inhibit T cell proliferation, has been concisely accomplished by a reactivity-based one-pot synthetic strategy under the use of p-toluenethioglycoside (STol) donors.

immunosuppressiveglycolipid simplexideone-pot glycosylationsynthesis

L(U), Guokai、WANG, Peng、LIU, Qingchao、ZHANG, Zaihong、ZHANG, Wei、LI, Yingxia

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Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy,Ocean University of China, Qingdao, Shandong 266003, China

Ph.D. Programs Foundation of Ministry of Education of China

20070423001

2009

中国化学(英文版)
中国化学会 上海有机化学研究所

中国化学(英文版)

CSCDSCI
影响因子:0.848
ISSN:1001-604X
年,卷(期):2009.27(11)
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