Nickel-Catalyzed Regioselective Hydrosilylation of Conjugated Dienest

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外文摘要：With the increasing demand for homoallylic silanes and allylic silanes,the highly efficient and regioselective hydrosilylations of conju-gated dienes are urgently needed.Herein,we developed a Ni-catalyzed regiodivergent hydrosilylation of aromatic conjugated dienes by adjusting the temperature and ligands.Under low temperature(-30 ℃),an eternal-ligand-free system(Ni/t-BuOK)can efficiently facilitate the 3,4-anti-Markovnikov hydrosilylation to provide homoallylic silanes via electrophilic activation process;under room temperature(25 ℃),a ligand-controlled system(Ni/t-BuOK/PPh3)can eventuate the 3,4-Markovnikov hydrosilylation to produce allylic silanes via Chalk-Harrod process.Both systems are compatible with various conjugated dienes and primary silanes in excellent yields and regioselectivities.

外文关键词：

Nickel-catalyzedRegioselective hydrosilylationConjugated dienesElectrophilic activationHomoallylic silanes

作者：

Xiaoyu Wu、Wei Liu、Liqun Yang、Yue Wang、Tianwen Liu、Yao Yuan、Yan Lu、Zhaoguo Zhang

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作者单位：

Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs,School of Chemistry and Chemical Engineering,Shanghai Jiao Tong University,800 Dongchuan Road,Shanghai 200240,China

Joseph Black Building,The University of Edinburgh,David Brewster Road,Edinburgh,EH9 3FJ,UK

基金：

国家自然科学基金

项目编号：

出版年：

2024

DOI：

10.1002/cjoc.202300407

中国化学(英文版)

中国化学会上海有机化学研究所

中国化学(英文版)

CSTPCD

影响因子：0.848

ISSN：1001-604X

年,卷(期)：2024.42(1)

参考文献量54