首页|Interfacing DNA and Aptamers with Gold Nanoparticles:From Fundamental Colloid and Interface Sciences to Biosensors

Interfacing DNA and Aptamers with Gold Nanoparticles:From Fundamental Colloid and Interface Sciences to Biosensors

扫码查看
Interfacing DNA oligonucleotides and DNA aptamers with gold nanoparticles has generated numerous functional hybrid materials for sensing,self-assembly and drug delivery applications.Our lab has been working in this area for 15 years.In this article,the current un-derstanding of the adsorption of DNA to gold nanoparticles is summarized,and related applications in bioconjugation of DNA to gold surface is described.In addition,problems of using gold nanoparticles to signaling aptamer binding are discussed.Finally,re-selection of aptamers for previously reported targets using the library-immobilization method is reviewed.

AptamersBiosensorsGold nanoparticlesSELEXBioconjugation

Yuzhe Ding、Juewen Liu

展开 >

Department of Chemistry,Waterloo Institute for Nanotechnology,University of Waterloo,Waterloo,Ontario,N2L3G1,Canada

2024

中国化学(英文版)
中国化学会 上海有机化学研究所

中国化学(英文版)

CSTPCD
影响因子:0.848
ISSN:1001-604X
年,卷(期):2024.42(19)