首页|Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario

Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario

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  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
Deep-sea mining activities can potentially release metals,which pose a toxicological threat to deep-sea ecosystems.Nevertheless,due to the remoteness and inaccessibility of the deep-sea biosphere,there is insufficient knowledge about the impact of metal exposure on its inhabitants.In this study,deep-sea mussel Gigantidas platifrons,a commonly used deep-sea toxicology model organism,was exposed to manganese(100,1 000 μg/L)or iron(500,5 000 μg/L)for 7 d,respectively.Manganese and iron were chosen for their high levels of occurrence within deep-sea deposits.Metal accumulation and a battery of biochemical biomarkers related to antioxidative stress in superoxide dismutase(SOD),catalase(CAT),malondialdehyde(MDA);immune function in alkaline phosphatase(AKP),acid phosphatase(ACP);and energy metabolism in pyruvate kinase(PK)and hexokinase(HK)were assessed in mussel gills.Results showed that deep-sea mussel G.platifrons exhibited a high capacity to accumulate Mn/Fe.In addition,most tested biochemical parameters were altered by metal exposure,demonstrating that metals could induce oxidative stress,suppress the immune system,and affect energy metabolism of deep-sea mussels.The integrated biomarker response(IBR)approach indicated that the exposure to Mn/Fe had a negative impact on deep-sea mussels,and Mn demonstrated a more harmful impact on deep-sea mussels than Fe.Additionally,SOD and CAT biomarkers had the greatest impact on IBR values in Mn treatments,while ACP and HK were most influential for the low-and high-dose Fe groups,respectively.This study represents the first application of the IBR approach to evaluate the toxicity of metals on deep-sea fauna and serves as a crucial framework for risk assessment of deep-sea mining-associated metal exposure.

musselmetaldeep-sea miningbiomarkerenvironmental monitoring

Li ZHOU、Mengna LI、Zhaoshan ZHONG、Minxiao WANG、Hao CHEN、Chao LIAN、Hao WANG、Huan ZHANG、Lei CAO、Chaolun LI

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Center of Deep Sea Research,Institute of Oceanology,Chinese Academy of Sciences,Qingdao 266071,China

CAS Key Laboratory of Marine Ecology and Environmental Sciences,Institute of Oceanology,Chinese Academy of Sciences,Qingdao 266071,China

University of Chinese Academy of Sciences,Beijing 100049,China

Laoshan Laboratory,Qingdao 266237,China

South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou 510301,China

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Marine Science and Technology Fund of Shandong Province for Qingdao Marine Science and Technology Center国家自然科学基金国家自然科学基金中国科学院战略规划重点项目中国科学院前沿科学重点研究计划国家重点研发计划

2022QNLM030004-14227615342030407XDB42020401ZDBS-LY-DQC0322022YFC2804003

2024

10.1007/s00343-023-3048-y

海洋湖沼学报(英文版)
中国海洋湖沼学会

海洋湖沼学报(英文版)

CSTPCD
影响因子：0.386
ISSN：2096-5508
年,卷(期)：2024.42(2)
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