首页|High-resolution portable lens-free on-chip microscopy with RGB LED via pinhole array

High-resolution portable lens-free on-chip microscopy with RGB LED via pinhole array

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Lens-free on-chip microscopy with RGB LEDs[LFOCM-RGB]provides a portable,cost-effective,and high-throughput imaging tool for resource-limited environments.However,the weak coherence of LEDs limits the high-resolution imaging,and the luminous surfaces of the LED chips on the RGB LED do not overlap,making the coherence-enhanced executions tend to undermine the portable and cost-effective implementation.Here,we propose a specially designed pinhole array to enhance coherence in a portable and cost-effective implementation.It modulates the three-color beams from the RGB LED sepa-rately so that the three-color beams effectively overlap on the sample plane while reducing the effective light-emitting area for better spatial coherence.The separate modulation of the spatial coherence allows the temporal coherence to be modu-lated separately by single spectral filters rather than by expensive triple spectral filters.Based on the pinhole array,the LFOCM-RGB simply and effectively realizes the high-resolution imaging in a portable and cost-effective implementation,offering much flexibility for various applications in resource-limited environments.

lens-free on-chip microscopyLEDphase retrievalpinhole array

王钦骅、马建设、曹良才、苏萍

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Tsinghua Shenzhen International Graduate School,Tsinghua University,Shenzhen 518055,China

Department of Precision Instrument,Tsinghua University,Beijing 100084,China

Shenzhen Key Basic ProgramShenzhen General Basic Program

JCYJ20200109143031287WDZC20220816110140002

2024

中国光学快报(英文版)
中国光学学会 中国科学院上海光学精密机械研究所

中国光学快报(英文版)

CSTPCD
影响因子:1.305
ISSN:1671-7694
年,卷(期):2024.22(2)
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