首页|皮肤肿瘤智能远程会诊系统研究

皮肤肿瘤智能远程会诊系统研究

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远程皮肤病学是缓解偏远地区皮肤专科医生缺乏问题的有效手段,但目前的方法存在适用范围有限、严重依赖远程医学专家及显示不够直观等缺陷。为弥补当前研究不足,设计并搭建了一套皮肤肿瘤智能远程会诊系统,该系统兼具无网络环境下的皮肤肿瘤自动筛查和有网络环境下的远程会诊及术前规划功能。性能量化实验结果表明,系统可将虚拟的标注高精度原位投射到成像区域。实验对照结果显示,部署于该系统的深度学习模型在诊断能力上与皮肤科专家相当,并且能够辅助专家更迅速、更精确地做出医疗决策。临床试验进一步证实了该系统的实用性。该系统旨在为医疗资源有限的地区提供帮助,使得当地患者能够进行皮肤肿瘤等多种疾病的早期筛查及治疗。
Intelligent Teleconsultation System for Skin Tumor
Objective Skin cancer is among the most common cancers worldwide.Skin cancer screening relies primarily on visual inspection by dermatologists,and largely depends on their experience.However,imbalances in regional development have led to an uneven distribution of medical resources worldwide.Telemedicine is an effective approach to alleviate this dilemma,and a major branch of this field is teledermatology.Dermatologists can remotely view clinical images and medical histories of skin cancer patients in various ways and provide remote diagnosis and treatment suggestions.However,teledermatology relies on medical experts and network conditions,and patients who cannot access the Internet in remote areas cannot enjoy the convenience of remote consultation.Some portable devices based on automatic diagnostic algorithms have made up for some shortcomings of traditional teledermatology;however,because they can only judge the type of disease,these devices have limited clinical applicability.To compensate for the shortcomings of the current research,our team design and build a skin tumor artificial intelligence-enhanced teleconsultation system,which has both offline automatic skin tumor screening and online remote consultation and preoperative planning functions.Methods In this study,we build a skin tumor intelligent teleconsultation system with two typical application scenarios:1)skin tumor self-screening without network conditions.Patients or doctors who lack experience at the local site can use the dermatoscope in the system to obtain images of skin lesions and then use the deep learning algorithm in the system to generate automatic diagnosis results.2)Remote skin tumor consultation under network conditions.Remote consultation for skin tumors involves real-time interactions among inexperienced doctors at a local site and experienced medical experts at a remote site.First,the doctor at the local site uses a dermatoscope or ordinary camera in the system to obtain skin images of patients with skin tumors.Then,the deep learning algorithm in the system generates automatic diagnosis results based on the images.Finally,the remote expert confirms the disease diagnosis result and recommends a corresponding treatment plan based on network-transmitted images and algorithmic cues.For patients requiring surgery,both parties can use the system for preoperative planning.Instructive annotations drawn by remote doctors on the screen are transmitted over the network to the local site and projected onto the body surface of the patient in situ.To achieve the above functions,we first train a RegNetY-800M model based on 7-point dataset and deploy it on Raspberry Pi,also using a neural network computing accelerator to accelerate neural network computation,then use camera,laser projector,and beam splitter to form a co-axial projective imaging design that can project instructive annotations made by remote experts with high accuracy onto patient's body surface,finally design a visual software interface for easy use by doctors.To characterize the system,we first design a benchtop experiment to quantify the achievable accuracy of the system,then design a control experiment to verify whether the system can improve the applicability and efficiency of the traditional teleconsultation system.Finally,a clinical experiment is designed to verify the clinical applicability of the system.Results and Discussions The benchtop experimental results show that the maximum projection error of the system is less than 1.5 mm(Fig.4),and the CIEDE2000 value after color correction is less than 2,which can accurately restore colors in the scene(Fig.5).The control experimental results show that there is no significant difference between the algorithm in the system and dermatologists;dermatologists perform better with AI prompts.Clinical experimental results show that using this system for automatic diagnosis and remote consultation of skin tumors is feasible.Conclusions The intelligent teleconsultation system for skin tumors designed and built by our team has both automatic disease screening without a network and remote consultation with the network.The control experimental results show that the diagnostic results of the algorithm deployed in the system are comparable to those of dermatologists and that the algorithm can help dermatologists make more efficient and accurate decisions.The experimental results show that the system has clinical applicability.Compared to traditional remote consultation systems,this system has the following three advantages.1)It has a wider application range.In remote areas without a network,the system can serve as a supplement to dermatologists,compensating for defects in which traditional teleconsultation systems cannot be used without a network.2)Better performance.Automatic diagnosis results in the system can assist specialists in a more efficient and accurate screening of skin tumors.3)Intuitive display.This system can project annotations made by remote experts onto body surfaces of patients with high precision,thereby making remote guidance in preoperative consultations and surgical planning processes more intuitive and precise.This system can help patients in areas with scarce medical resources perform early screening for various diseases,such as skin tumors.

medical opticsbiotechnologyteledermatologyartificial intelligenceaugmented realityco-axial projective imaging

郎中亮、张帆、吴柄萱、邵鹏飞、申书伟、姚鹏、刘鹏、徐晓嵘

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中国科学技术大学生物医学工程学院,安徽合肥 230026

中国科学技术大学附属第一医院(安徽省立医院)整形外科,安徽合肥 230001

中国科学技术大学精密机械与精密仪器系,安徽合肥 230027

中国科学技术大学苏州高等研究院,江苏苏州 215123

中国科学技术大学电子科学与技术系,安徽合肥 230026

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医用光学 生物技术 远程皮肤病学 人工智能 增强现实 原位投影成像

江苏省自然科学基金面上项目

BK20231213

2024

中国激光
中国光学学会 中科院上海光机所

中国激光

CSTPCD北大核心
影响因子:2.204
ISSN:0258-7025
年,卷(期):2024.51(9)
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