Comparison Between Q-Switched 694 Laser and Q-Switched 532 Laser for Clinical Efficacy of Freckle Treatment
Objective To compare the clinical efficacy and safety of 694 nm and 532 nm QS neodymium-doped yttrium aluminum garnet lasers in treating freckles.Methods Totally 211 patients with freckles were randomly divided into two groups,namely,group A (112 cases) and group B (99 cases),to compare the clinical efficacy and safety of the treatment.While the patients in group A being treated with QS694 laser once,those of group B were given QS532 laser treatment once.The efficacy and safety were evaluated 30 days after the final treatment.Results After one time treatment,the effective rate of group A was 99% (complete disappearance for 106 patients,significant improvementfor 5 patients and moderate improvement for 1 patient),and that of group B was 93% (complete disappearance for 87 patients,significant improvement for 5 patients,moderate improvement for 6 patients and no improvement for 1 patient).The difference was statistically significant (P < 0.05).Color-offoccurred to 2 patients in group A and 6 patients in group B respectively,pigmentation to 5 patients in group A and 9 patients in group B respectively.Indicating that difference between them in the adverse reactions was significant (P < 0.05).Conclusions Both 694 nm and 532 nm QS lasers will reduce freckles effectively with high patient satisfaction.The efficacy and safety of QS694 laser is better than that of QS532 laser.Adverse reactions of 694 nm laser were less than that of 532 nm laser.