Occurrence and Influencing Factors of Macular Edema after Intraocular Lens Implantation and Laser Treatment in Patients with Diabetes Retinopathy
Objective To analyze the incidence and influencing factors of macular edema in patients with diabetes retinopathy(DR)after intraocular lens implantation and laser treatment.Methods Totally 110 non-proliferative DR patients with monocular onset were prospectively selected,all given single focal intraocular lens implantation and 3 laser treatments.The macular edema status of all the patients was statistically analyzed 3 months after the treatment,and then they were divided into an edema group and a non-edema group based on macular edema status.All the factors leading to macular edema to the patients were considered and both univariate and multivariate statistical analysis were conducted to identify factors relating to the occurrence of macular edema in DR patients given both intraocular lens implantation and laser therapy.Results Three months after the treatment,17 of the 110 non-proliferative DR patients given both intraocular lens implantation and laser therapy suffered macular edema,indicating an incidence rate of 15.5％.There were significant differences in course of diabetes,DR stage,glycosylated hemoglobin(HbAlc)and interleukin-6(IL-6)levels between the edematous group and non-edematous group(P＜O.05),but the difference between the two groups in gender,age,smoking,drinking,diabetes type,insulin use and total cholesterol levels was not remarkable(P＞0.05).It was shown via regression analysis that the overexpression of HbAlc and IL-6,long duration of diabetes and stage Ⅲ of DR were the influencing factors of macular edema in DR patients given both intraocular lens implantation and laser treatment(OR＞1,P＜0.05).Conclusions The risk of macular edema in DR patients given both intraocular lens implantation and laser treatment is high.Overexpression of HbAlc and IL-6,long course of diabetes and DR stage Ⅲ are all influencing factors of macular edema.
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