Research Progress of Non-Damage Phototherapy Regulating Dermal Fibroblasts in the Healing Process of Diabetic Foot Ulcer
Diabetes foot(DF)is one of the most serious chronic complications of diabetes.diabetes foot ulcers(DFUs)have a direct impact on the amputation rate and survival rate of diabetes patients.As the most abundant cells in the dermis,dermal fibroblasts play a key role in the healing process of DFUs.At present,there is no specific and effective treatment method for DFUs.Increasing the function of dermal fibroblasts to promote ulcer healing is an effective treatment strategy.Non-damage phototherapy(NDPT),as a non-invasive,non-toxic side effects and a non-contact new adjuvant treatment method,has great application potential in the treatment of DFUs.This article reviews the abnormal changes of dermal fibroblasts in DFUs,the basic and clinical research progress of NDPT in treating DFUs by regulating dermal fibroblasts.