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中国2022年百日咳流行病学特征

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目的 分析中国2022年百日咳流行病学特征.方法 通过中国疾病预防控制信息系统收集2022年百日咳报告病例信息,描述性分析流行病学特征.结果 中国2022年报告百日咳38 295例,报告发病率为2.71/10万;自2018年以来报告发病率年均增长14.26%.0-4岁、5-9岁、10-14岁、≥ 15岁病例分别占总病例数的52.67%、40.27%、5.37%、1.69%;在 0 岁病例中,0-2 月龄、3-5 月龄、6-11 月龄分别占 40.63%、41.54%、17.83%.在 28 500例获得百白破联合疫苗(Diphtheria,tetanus and pertussis combined vaccine,DTP)接种记录的病例中,发病前接种0剂次、1-2剂次、3剂次、4剂次者分别占19.05%、7.91%、7.87%、65.18%,其中在3-5月龄病例中分别占49.49%、49.28%、1.23%、0.00%,在5-9岁病例中分别占0.07%、0.02%、4.75%、95.16%.结论 中国2022年百日咳报告发病率大幅上升,发病以0-9岁儿童特别是无DTP接种史或未完成3剂次接种的婴儿为主.建议加强适龄儿童及时和全程接种DTP,推进儿童百日咳疫苗免疫策略优化研究.
Epidemiological characteristics of pertussis in China,2022
Objective To describe epidemiological characteristics of pertussis in China in 2022.Methods We collected data on pertussis cases that were reported to the China Disease Control and Prevention Information System in 2022 and conducted a descriptive epidemiological analysis.Results A total of 38 295 pertussis cases were reported in China in 2022,for an overall incidence of 2.71 cases per 100 000 population and an annual increase in incidence of 14.26%since 2018;0-4-,5-9-,10-14-,and≥ 15-year-olds accounted for 52.67%,40.27%,5.37%,and 1.69%of all cases,respectively;0-2-,3-5-,and 6-11-month-olds accounted for 40.63%,41.54%and 17.83%of infant cases.Among the 28 500 cases with diphtheria,tetanus,and pertussis combined vaccine(DTP)vaccination records,19.05%,7.91%,7.87%,and 65.18%cases had received 0,1-2,3,or 4 doses of DTP before pertussis onset;respective number of doses among 3-5-month-old cases were 49.49%,49.28%,1.23%,and 0.00%,and among 5-9-year-old cases were 0.07%,0.02%,4.75%,and 95.16%.Conclusions The reported incidence of pertussis increased significantly in 2022 in China and was highest among children 0-9 years of age,particularly among infants who had not received DTP or had received fewer than 3 doses.We suggest enhancing timely and full-series pertussis vaccination for age-eligible children and promoting research on optimizing childhood pertussis immunization strategies.

PertussisEpidemiological characteristics

张倩、吴丹、郑徽、李明爽、闫婷婷、尹遵栋、李艺星

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传染病溯源预警与智能决策全国重点实验室,中国疾病预防控制中心,北京 102206

中国疾病预防控制中心免疫规划中心,北京 100050

百日咳 流行病学特征

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102393220020010000017

2024

中国疫苗和免疫
中国疾病预防控制中心

中国疫苗和免疫

CSTPCD北大核心
影响因子:2.311
ISSN:1006-916X
年,卷(期):2024.30(1)
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